C₂₆H₃₀N₈O₇S

Base Information

• Chemical Name: C₂₆H₃₀N₈O₇S
• CAS No.: 1380111-12-5
• Molecular Formula: C₂₆H₃₀N₈O₇S
• Molecular Weight: 598.64
• Mol file: 1380111-12-5.mol

Synonyms:C₂₆H₃₀N₈O₇S

Chemical Property of C₂₆H₃₀N₈O₇S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₆H₃₀N₈O₇S

There total 11 articles about C₂₆H₃₀N₈O₇S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

C33H37N5O10S2 (1380111-11-4) → C26H30N8O7S (1380111-12-5)

Guidance literature:

With tetrabutylammoniun azide; tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; at 20 - 25 ℃; for 13h;

Reference yield:

di-tert-butyl dicarbonate (24424-99-5) → C26H30N8O7S (1380111-12-5)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridine / dichloromethane / 20 °C

2: sodium hydroxide / ethanol / 0.5 h / 20 - 50 °C

3: methanol / 40 °C / 17 Torr

4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 13 h / 20 °C

5: tetrabutylammoniun azide; tetra-(n-butyl)ammonium iodide / tetrahydrofuran / 13 h / 20 °C

With pyridine; tetrabutylammoniun azide; tetra-(n-butyl)ammonium iodide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm400560z

Reference yield:

ethyl 2-(2-aminothiazol-4-yl)glyoxylate (64987-08-2) → C26H30N8O7S (1380111-12-5)

Guidance literature:

Multi-step reaction with 5 steps

1: pyridine / dichloromethane / 20 °C

2: sodium hydroxide / ethanol / 0.5 h / 20 - 50 °C

3: methanol / 40 °C / 17 Torr

4: O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 13 h / 20 °C

5: tetrabutylammoniun azide; tetra-(n-butyl)ammonium iodide / tetrahydrofuran / 13 h / 20 °C

With pyridine; tetrabutylammoniun azide; tetra-(n-butyl)ammonium iodide; O-(1H-benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium hexafluorophosphate; N-ethyl-N,N-diisopropylamine; sodium hydroxide; In tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jm400560z

upstream raw materials:

C₃₃H₃₇N₅O₁₀S₂

di-tert-butyl dicarbonate

ethyl 2-(2-aminothiazol-4-yl)glyoxylate

1-hydroxycyclobutane-1-carbonitrile

Downstream raw materials:

C₂₆H₃₂N₆O₇S

C₄₈H₅₀N₁₀O₁₀S

C₄₇H₅₀N₈O₁₁S

Refernces

• 1、 -. "MONOBACTAMS". Page/Page column 122-123. . Retrieved 2012/06/16.