methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate

Base Information

• Chemical Name: methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate
• CAS No.: 94354-81-1
• Molecular Formula: C₂₈H₄₀O₅S
• Molecular Weight: 488.689
• Mol file: 94354-81-1.mol

Synonyms:methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate

Chemical Property of methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate

There total 3 articles about methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

14β-hydroxymethyl-8,13-dimethyl-podocarp-12-en-16-oic acid methyl ester (94354-80-0) + p-toluenesulfonyl chloride (98-59-9) → methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate (94354-81-1)

Guidance literature:

With pyridine; at 0 ℃; for 48h;

Reference yield:

agathic acid 15-methyl ester (14027-05-5) → methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate (94354-81-1)

Guidance literature:

Multi-step reaction with 3 steps

1: 99 percent / 98percent aq. formic acid / 7 h / 70 °C

2: 1.) LiAlH₄ / 1) diethyl ether, 4h, room temp. 2) diethyl ether

3: 98 percent / pyridine / 48 h / 0 °C

With pyridine; lithium aluminium tetrahydride; formic acid;

Reference yield:

(+) O-15-methyl isoagathate (94354-75-3) → methyl ent-15-hydroxyisocopal-12-en-19-oate tosylate (94354-81-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 1.) LiAlH₄ / 1) diethyl ether, 4h, room temp. 2) diethyl ether

2: 98 percent / pyridine / 48 h / 0 °C

With pyridine; lithium aluminium tetrahydride;

upstream raw materials:

14β-hydroxymethyl-8,13-dimethyl-podocarp-12-en-16-oic acid methyl ester

p-toluenesulfonyl chloride

agathic acid 15-methyl ester

(+) O-15-methyl isoagathate

Refernces