2-CHLORO-3-PHENYLPROPIONITRILE

Base Information

• Chemical Name: 2-CHLORO-3-PHENYLPROPIONITRILE
• CAS No.: 17849-62-6
• Molecular Formula: C9H8ClN
• Molecular Weight: 165.622
• Hs Code.: 2926909090
• Mol file: 17849-62-6.mol

Synonyms:2-Chlor-3-phenyl-propionitril;(2S)-2-chloro-3-phenylpropanenitrile;2-Chloro-3-phenylpropionitrile;(+-)-2-Chlor-3-phenyl-propionsaeure-nitril;

Chemical Property of 2-CHLORO-3-PHENYLPROPIONITRILE

Chemical Property:

• Vapor Pressure: 0.00305mmHg at 25°C
• Boiling Point: 284.1°C at 760 mmHg
• Flash Point: 123°C
• PSA: 23.79000
• Density: 1.15g/cm³
• LogP: 2.36008

Purity/Quality:

98.00% ^*data from raw suppliers

2-Chloro-3-phenyl-propionitrile 95%+ ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-CHLORO-3-PHENYLPROPIONITRILE

There total 12 articles about 2-CHLORO-3-PHENYLPROPIONITRILE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

→ 2-chloro-3-phenylpropionitrile (17849-62-6)

Guidance literature:

Reference yield:

phenyl acetaldehyde cyanohydrin (50353-47-4) → 2-chloro-3-phenylpropionitrile (17849-62-6)

Guidance literature:

With 3-ethyl-2-chlorobenzoxazolium tetrafluoroborate; tetraethylammonium chloride; triethylamine; In dichloromethane;

DOI:10.1246/cl.1979.1117

Reference yield:

acrylonitrile (107-13-1,25014-41-9) + aniline (62-53-3) → 2-chloro-3-phenylpropionitrile (17849-62-6) + chlorobenzene (108-90-7)

Guidance literature:

With tert-Butyl thionitrate; copper dichloride; In acetonitrile;

DOI:10.1246/bcsj.53.1065

upstream raw materials:

sodium acetate

benzene diazonium chloride

acrylonitrile

phenyl acetaldehyde cyanohydrin

Downstream raw materials:

N-phenyl-DL-phenylalanine

2-Nitro-2-cyano-1-phenyl-ethan

2-(1-Cyano-2-phenyl-ethylsulfanyl)-3-phenyl-propionitrile

cinnamic nitrile

Refernces

• 1、 -. "Arylation of olefins". . . Retrieved 2008/06/13.
• 2、 -. "Process for producing a halogen-containing ethylbenzene derivative". . . Retrieved 2008/06/13.