Benzene, 1-fluoro-2,4-dimethyl-5-nitro-

Base Information

• Chemical Name: Benzene, 1-fluoro-2,4-dimethyl-5-nitro-
• CAS No.: 345-22-2
• Molecular Formula: C8H8 F N O2
• Molecular Weight: 169.155
• Hs Code.: 2904990090
• Mol file: 345-22-2.mol

Synonyms:m-Xylene,4-fluoro-6-nitro- (7CI,8CI); 1-Fluoro-2,4-dimethyl-5-nitrobenzene; NSC 207869

Chemical Property of Benzene, 1-fluoro-2,4-dimethyl-5-nitro-

Chemical Property:

• Vapor Pressure: 0.04mmHg at 25°C
• Boiling Point: 247.6°Cat760mmHg
• Flash Point: 103.5°C
• PSA: 45.82000
• Density: 1.225g/cm³
• LogP: 2.87390
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

98%min ^*data from raw suppliers

1-Fluoro-2,4-dimethyl-5-nitrobenzene ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Benzene, 1-fluoro-2,4-dimethyl-5-nitro-

There total 1 articles about Benzene, 1-fluoro-2,4-dimethyl-5-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 1-fluoro-2,4-dimethyl-5-nitro-benzene (345-22-2)

Guidance literature:

DOI:10.1021/ja01346a050

Reference yield:

1-fluoro-2,4-dimethyl-5-nitro-benzene (345-22-2) + 3,5-bis(trifluoromethyl)-1H-1,2,4-triazole (709-62-6,154445-76-8) → 1-(2-fluoro-5-methyl-4-nitrobenzyl)-3,5-bis(trifluoromethyl)-1H-1,2,4-triazole (1207089-57-3) + 1-(4-fluoro-5-methyl-2-nitrobenzyl)-3,5-bis(trifluoromethyl)-1H-1,2,4-triazole (1207089-56-2)

Guidance literature:

1-fluoro-2,4-dimethyl-5-nitro-benzene; With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); In tetrachloromethane; for 6h; Reflux; lighting;

3,5-bis(trifluoromethyl)-1H-1,2,4-triazole; With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 1h;

Reference yield:

1-fluoro-2,4-dimethyl-5-nitro-benzene (345-22-2) → 1-bromo-2-chloro-6-fluoro-3,5-dimethyl-4-nitro-benzene (436-58-8)

Guidance literature:

Multi-step reaction with 4 steps

1: iron; aqueous hydrochloric acid

2: acetic acid; bromine

3: sulfuric acid; nitric acid

4: aqueous HCl / Diazotization_.Behandlung der Diazoniumsalz-Loesung mit CuCl

With hydrogenchloride; sulfuric acid; bromine; nitric acid; iron; acetic acid;

DOI:10.1021/ja01346a050

Downstream raw materials:

5-fluoro-2,4-dimethylaniline

5-fluoro-2,4-dimethyl-phenol

2-bromo-3-fluoro-4,6-dimethyl-phenol

2-bromo-3-fluoro-4,6-dimethyl-aniline