Dipivefrin

Base Information

• Chemical Name: Dipivefrin
• CAS No.: 52365-63-6
• Molecular Formula: C19H29 N O5
• Molecular Weight: 351.443
• Hs Code.: 2922509090
• UNII: 8Q1PVL543G
• DSSTox Substance ID: DTXSID1048544
• Nikkaji Number: J2.819.745D
• Wikipedia: Dipivefrine
• Wikidata: Q905952
• NCI Thesaurus Code: C61729
• Pharos Ligand ID: LPZNKD6TMA9G
• Metabolomics Workbench ID: 42803
• ChEMBL ID: CHEMBL1201262
• Mol file: 52365-63-6.mol

Synonyms:(+)-dipivefrin;(-)-dipivefrin;(R)-dipivefrine;(RS)-4-(1-hydroxy-2-(methylamino)ethyl)-O-phenylene dipivalate hydrochloride;(S)-dipivefrin;(S)-dipivefrine;adrenaline dipivalate;Akpro;Apo-Dipivefrin;d Epifrin;Diopine;dipivaloylepinephrine;dipivalyl epinephrine;dipivefrin;dipivefrin acetate, (+-)-isomer;dipivefrin citrate (1:1), (+-)-isomer;dipivefrin HCl;dipivefrin hydrochloride;dipivefrin hydrochloride, (+-)-isomer;dipivefrin hydrochloride, (R)-;dipivefrin hydrochloride, (S)-;dipivefrin monophosphate, (+-)-isomer;dipivefrin monosulfate, (+-)-isomer;dipivefrin nitrate, (+-)-isomer;dipivefrin perchlorate;dipivefrin propanoate, (+-)-isomer;dipivefrin tartrate (1:1), (+-)-(R-(R*,R*))-isomer;dipivefrin tartrate (1:1), (R)-(R-(R*,R*))-isomer;dipivefrin, (R)-isomer;dipivefrine;dipivefrine hydrochloride;dipivefrine hydrochloride, (R)-;dipivefrine hydrochloride, (S)-;dipivefrine, (R)-;Dipoquin;Glaucothil;Glaudrops;PMS-Dipivefrin;propanoic acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ester, (+-)-;propanoic acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ester, (R)-;propanoic acid, 2,2-dimethyl-, 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene ester, (S)-;Propine;ratio-Dipivefrin

Chemical Property of Dipivefrin

Chemical Property:

• Vapor Pressure: 8.89E-10mmHg at 25°C
• Melting Point: 146-147°
• Boiling Point: 473.7 °C at 760 mmHg
• PKA: pKa 8.40(RT) (Uncertain)
• Flash Point: 240.3 °C
• PSA: 84.86000
• Density: 1.097 g/cm³
• LogP: 3.23330
• XLogP3: 2.9
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 9
• Exact Mass: 351.20457303
• Heavy Atom Count: 25
• Complexity: 463

Purity/Quality:

98%Min ^*data from raw suppliers

Dipivefrin ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC(C)(C)C(=O)OC1=C(C=C(C=C1)C(CNC)O)OC(=O)C(C)(C)C
• Recent NIPH Clinical Trials: Pupillary autonomic dysfunction and visual hallucination in Parkinson's disease
• Uses: Adrenergic (ophthalmic).
• Therapeutic Function: Adrenergic (ophthalmic)

Technology Process of Dipivefrin

There total 1 articles about Dipivefrin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 4-(1-hydroxy-2-(methylamino)ethyl)-1,2-phenylene bis(2,2-dimethylpropanoate) (52365-63-6)

Guidance literature:

Aus 1-(3',4'-Dipivaloyloxyphenyl)-2-(N-benzylaminomethyl)-ethan-1-on u. H2;