Corticorelin

Base Information

• Chemical Name: Corticorelin
• CAS No.: 86784-80-7
• Deprecated CAS: 86297-72-5
• Molecular Formula: C208H344N60O63S2
• Molecular Weight: 4757.45
• Hs Code.: 2937190000
• ChEMBL ID: CHEMBL2107324
• NCI Thesaurus Code: C394
• Wikipedia: Corticorelin
• Mol file: 86784-80-7.mol

Synonyms:Corticorelin;NEU 3002;Xerecept;Corticobiss;Human corticorelin;Human CRF;Rat CRF;Corticorelin [INN];Rat hypothalamic CRF;Corticorelin acetate human;Human CRF (1-41);NEU-3002 ACETATE;Rat CRF(1-41);CCRIS 5322;CRF 41;CHEMBL2107324;UNII-305OE8862Y;MCI 028;CHEBI:136037;Rat corticotropin-releasing factor;Human corticotropin-releasing factor;Corticotropin-releasing factor (rat);Rat corticotropin-releasing factor-41;AKOS024456419;Corticotropin-releasing factor (horse);305OE8862Y;Corticotropin-Releasing Factor (human, rat);Corticotropin-releasing factor (sheep), 2-L-glutamic acid-22-L-alanine-23-L-arginine-25-L-glutamic acid-38-L-methionine-39-L-glutamic acid-41-L-isoleucinamide-

Chemical Property of Corticorelin

Chemical Property:

• PSA: 2049.59000
• LogP: 5.89730
• Storage Temp.: −20°C
• XLogP3: -14.3
• Hydrogen Bond Donor Count: 67
• Hydrogen Bond Acceptor Count: 72
• Rotatable Bond Count: 166
• Exact Mass: 4756.5067243
• Heavy Atom Count: 333
• Complexity: 11700

Purity/Quality:

99% ^*data from raw suppliers

Corticotropin Releasing Factor ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CCC(C)C(C(=O)N)NC(=O)C(C(C)CC)NC(=O)C(CCC(=O)O)NC(=O)C(CCSC)NC(=O)C(CC(C)C)NC(=O)C(CCCCN)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(=O)N)NC(=O)C(CO)NC(=O)C(CC1=CNC=N1)NC(=O)C(C)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)N)NC(=O)C(C)NC(=O)C(CC(C)C)NC(=O)C(CCC(=O)N)NC(=O)C(CCC(=O)O)NC(=O)C(C)NC(=O)C(CCCNC(=N)N)NC(=O)C(C)NC(=O)C(CCSC)NC(=O)C(CCC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(C(C)C)NC(=O)C(CCC(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CC(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC2=CNC=N2)NC(=O)C(CC3=CC=CC=C3)NC(=O)C(C(C)O)NC(=O)C(CC(C)C)NC(=O)C(CC(=O)O)NC(=O)C(CC(C)C)NC(=O)C(CO)NC(=O)C(C(C)CC)NC(=O)C4CCCN4C(=O)C5CCCN5C(=O)C(CCC(=O)O)NC(=O)C(CCC(=O)O)NC(=O)C(CO)N
• Isomeric SMILES: CC[C@H](C)[C@@H](C(=O)N)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCCCN)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(=O)N)NC(=O)[C@H](CO)NC(=O)[C@H](CC1=CNC=N1)NC(=O)[C@H](C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CCC(=O)N)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](C)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](C)NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](C(C)C)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCCNC(=N)N)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC2=CNC=N2)NC(=O)[C@H](CC3=CC=CC=C3)NC(=O)[C@H]([C@@H](C)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CC(=O)O)NC(=O)[C@H](CC(C)C)NC(=O)[C@H](CO)NC(=O)[C@H]([C@@H](C)CC)NC(=O)[C@@H]4CCCN4C(=O)[C@@H]5CCCN5C(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CCC(=O)O)NC(=O)[C@H](CO)N
• Recent ClinicalTrials: Hormonal Mechanisms of Sleep Restriction - Axis Study
• Recent EU Clinical Trials: Effects of corticotropin-releasing hormone on sleep electroencephalogram and sleep associated hormone secretion in young healthy women
• Uses: Treatment of symptoms associated with peritumoral edema in brain tumor patients. Corticotropin Releasing Factor human, rat has been used:as a component in Dulbecco′s modified eagle medium (DMEM) for incubating lung explantsas a component in serum-free complete medium for isolation and culturing of fetal distal lung epithelial cellsin the synthesis of the corticotropin-releasing factor(CRF)-TAMRA?1?mixturein chronic intracerebroventicular administration, to study its effect on hypoxia in hippocampus