Gallium citrate

Base Information

• Chemical Name: Gallium citrate
• CAS No.: 27905-02-8
• Molecular Formula: C6H8 O7 . Ga
• Molecular Weight: 258.83
• European Community (EC) Number: 248-721-1
• UNII: HT6C49L0ZP
• DSSTox Substance ID: DTXSID50952742
• Nikkaji Number: J71.258B
• Mol file: 27905-02-8.mol

Synonyms:(68)Ga-citrate;Ga-67 citrate;gallium citrate;gallium citrate (1:1);67Ga-labeled;gallium citrate, 67Ga-labeled;gallium(67) citrate;gallium-67-citrate

Chemical Property of Gallium citrate

Chemical Property:

• Vapor Pressure: 5.73E-05mmHg at 25°C
• Boiling Point: 309.6°Cat760mmHg
• Flash Point: 155.2°C
• PSA: 132.13000
• Density: g/cm³
• LogP: -1.29180
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 257.92910
• Heavy Atom Count: 14
• Complexity: 211

Purity/Quality:

99%, ^*data from raw suppliers

GALLIUM CITRATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Metals -> Organic Acids, Metal Salts
• Canonical SMILES: C(C(=O)[O-])C(CC(=O)[O-])(C(=O)[O-])O.[Ga+3]
• Recent ClinicalTrials: A Feasibility Study of Gallium-68 Citrate PET to Detect Aberrant MYC Proto-Oncogene, BHLH Transcription Factor (MYC) Protein Expression in Diffuse Large B-Cell Lymphoma
• Uses: Gallium is likewise very sensitive in detecting and locating infections and inflammatory foci (interstitial lung disease, chronic hepatitis, pulmonary disease, sarcoidosis, osteomyelitis, etc.). This application is extremely important in the management of immunocompromised cancer patients. Because AIDS patients frequently present minimal symptomatology, radionuclide imaging, with its ability to survey the entire body, is especially valuable, and also in labeled leukocyte scintigraphy. Image interpretation should be tempered by full knowledge of the patient’s clinical condition, anatomic alterations due to prior surgery, and correct timing of image acquisition. Early imaging at 4–6 h is useful in the detection of gastrointestinal infections, whereas 24 h imaging is useful in the evaluation of chest infections. Although 67Ga is a nonspecific agent, the identification of the etiology of the inflammationmay be improved by appropriate clinical and laboratory information as well as by correlation with other imaging modalities such as sonography and computerized X-ray tomography (CT). High-dose (10mCi) 67Ga single-photon emission computed tomography (SPECT) imaging with image coregistration is important for accurate uptake localization.