C₁₆H₁₄BrN

Base Information

• Chemical Name: C₁₆H₁₄BrN
• CAS No.: 1386384-19-5
• Molecular Formula: C₁₆H₁₄BrN
• Molecular Weight: 300.198
• Mol file: 1386384-19-5.mol

Synonyms:C₁₆H₁₄BrN

Chemical Property of C₁₆H₁₄BrN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₆H₁₄BrN

There total 4 articles about C₁₆H₁₄BrN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

C22H18BrNO2S (1386384-18-4) → C16H14BrN (1386384-19-5)

Guidance literature:

With water; sodium hydroxide; In methanol; Reflux; Inert atmosphere;

DOI:10.1021/ol301663h

Reference yield:

C22H16BrNO2S (1386384-17-3) → C16H14BrN (1386384-19-5)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

2: water; sodium hydroxide / methanol / Reflux; Inert atmosphere

With palladium on activated charcoal; water; hydrogen; sodium hydroxide; In methanol; ethyl acetate;

DOI:10.1021/ol301663h

Reference yield:

1-(phenylsulfonyl)indole-3-carbaldehyde (80360-20-9) → C16H14BrN (1386384-19-5)

Guidance literature:

Multi-step reaction with 3 steps

1: potassium tert-butylate / tetrahydrofuran / 20 °C / Inert atmosphere

2: palladium on activated charcoal; hydrogen / ethyl acetate / 20 °C

3: water; sodium hydroxide / methanol / Reflux; Inert atmosphere

With palladium on activated charcoal; potassium tert-butylate; water; hydrogen; sodium hydroxide; In tetrahydrofuran; methanol; ethyl acetate; 1: Wittig olefination;

DOI:10.1021/ol301663h

upstream raw materials:

C₂₂H₁₆BrNO₂S

C₂₂H₁₈BrNO₂S

1-(phenylsulfonyl)indole-3-carbaldehyde

(2-bromobenzyl)triphenylphosphonium bromide

Downstream raw materials:

C₁₆H₁₅N

5,6-dihydro-11H-benzo[a]carbazole

Refernces