4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium

Base Information

• Chemical Name: 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium
• CAS No.: 639010-33-6
• Molecular Formula: C₁₇H₁₄F₃N₃O₂S*HNa
• Molecular Weight: 405.376
• Mol file: 639010-33-6.mol

Synonyms:4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium

Chemical Property of 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium

There total 3 articles about 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide (169590-42-5,194044-54-7) → 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium (639010-33-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 20 ℃; for 0.0833333h;

Reference yield:

4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione (720-94-5) → 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium (639010-33-6)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / Reflux

2: sodium hydroxide / water; ethanol / 0.08 h / 20 °C

With sodium hydroxide; In ethanol; water;

Reference yield:

para-methylacetophenone (122-00-9) → 4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)benzenesulfonamide sodium (639010-33-6)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium methylate / methanol; tert-butyl methyl ether / 20 °C / Inert atmosphere

1.2: 20 °C

2.1: ethanol / Reflux

3.1: sodium hydroxide / water; ethanol / 0.08 h / 20 °C

With sodium methylate; sodium hydroxide; In methanol; ethanol; tert-butyl methyl ether; water;

upstream raw materials:

para-methylacetophenone

4,4,4-trifluoro-1-(4-methylphenyl)butane-1,3-dione

4-[5-(4-(methyl)phenyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl]benzenesulphonamide

Downstream raw materials:

(Z)-1-((1,3-dioxoisoindolin-2-yl)methoxy)-3-methyl-3-(2-oxo-2-(4-(5-(p-tolyl)-3-(trifluoromethyl)-1H-pyrazol-1-yl)phenylsulfonamido)ethyl)triaz-1-ene 2-oxide

Refernces