Domperidone Maleate

Base Information

• Chemical Name: Domperidone Maleate
• CAS No.: 99497-03-7
• Molecular Formula: C22H24ClN5O2^.C4H4O4
• Molecular Weight: 541.98
• European Community (EC) Number: 281-277-7,801-827-7
• UNII: 899U5WF46A
• DSSTox Substance ID: DTXSID901019221
• Wikidata: Q27126907
• ChEMBL ID: CHEMBL3436365
• Mol file: 99497-03-7.mol

Synonyms:Apo Domperidone;Apo-Domperidone;Domidon;Domperidon;Domperidon AL;Domperidon Hexal;Domperidon Stada;Domperidon TEVA;Domperidon-TEVA;Domperidona Gamir;Domperidone;Domperidone Maleate;Domperidone Maleate (1:1);Domperidone Monohydrochloride;Gamir, Domperidona;Gastrocure;Hexal, Domperidon;Maleate, Domperidone;Monohydrochloride, Domperidone;Motilium;Nauzelin;Novo Domperidone;Novo-Domperidone;Nu Domperidone;Nu-Domperidone;Péridys;PMS Domperidone;PMS-Domperidone;R-33,812;R-33812;R33,812;R33812;ratio Domperidone;ratio-Domperidone;Stada, Domperidon

Chemical Property of Domperidone Maleate

Chemical Property:

• Vapor Pressure: 1.62E-25mmHg at 25°C
• Melting Point: 236 - 239 °C
• Boiling Point: 778.5 °C at 760 mmHg
• Flash Point: 424.7 °C
• PSA: 153.42000
• LogP: 3.00290
• Storage Temp.: Hygroscopic, -20°C Freezer, Under inert atmosphere
• Solubility.: Very slightly soluble in water, sparingly soluble in dimethylformamide, slightly soluble in methanol, very slightly soluble in ethanol (96 per cent).
• Hydrogen Bond Donor Count: 4
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 7
• Exact Mass: 541.1728113
• Heavy Atom Count: 38
• Complexity: 774

Purity/Quality:

99%, ^*data from raw suppliers

Domperidone maleate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O.C(=CC(=O)O)C(=O)O
• Isomeric SMILES: C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O.C(=C\C(=O)O)\C(=O)O
• Recent ClinicalTrials: Enhancing Breast Milk Production With Domperidone in Mothers of Preterm Neonates
• Recent EU Clinical Trials: Gastromotal 13C-octanoic acid breath test in the diagnosis and evaluation of therapeutic outcome in patients with dyspeptic symptoms and delayed gastric emptying
• Uses: Domperidone maleate (CAS# 99497-03-7); a form of Domperidone (D531100), a novel peripheral dopamine receptor antagonist that does not cross the blood-brain barrier; anti-emetic. Domperidone(Motilium) is a dopamine blocker and an antidopaminergic reagent. Anti-emetic, Dopaminergic blocking agent