α-(2,6-dimethylphenyl)vinyl bromide

Base Information

• Chemical Name: α-(2,6-dimethylphenyl)vinyl bromide
• CAS No.: 74331-78-5
• Molecular Formula: C₁₀H₁₁Br
• Molecular Weight: 211.101
• Mol file: 74331-78-5.mol

Synonyms:α-(2,6-dimethylphenyl)vinyl bromide

Chemical Property of α-(2,6-dimethylphenyl)vinyl bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of α-(2,6-dimethylphenyl)vinyl bromide

There total 10 articles about α-(2,6-dimethylphenyl)vinyl bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.5%

2,6-dimethylphenylacetylene (74331-74-1) → α-(2,6-dimethylphenyl)vinyl bromide (74331-78-5)

Guidance literature:

With hydrogen bromide; In chloroform;

DOI:10.1021/ja00400a047

Reference yield: 61.0%

2',6'-dimethylacetophenone (2142-76-9) → α-(2,6-dimethylphenyl)vinyl bromide (74331-78-5)

Guidance literature:

With α,α-dibromomethyl methyl ether; In chloroform; at 100 ℃; for 4h;

DOI:10.1055/s-1993-25986

Reference yield: 60.0%

2',6'-dimethylacetophenone (2142-76-9) → α-(2,6-dimethylphenyl)vinyl bromide (74331-78-5) + 2-bromo-2',6'-dimethylacetophenone (2633-42-3)

Guidance literature:

With 2,2,2-tribromo-1,3,2-benzodioxaphosphole; In chloroform; at 80 ℃; for 4h;

DOI:10.1055/s-1993-25986

upstream raw materials:

2',6'-dimethylacetophenone

2,6-dimethylphenylacetylene

2,6-dimethylbenzonitrile

1-(2,6-dimethylphenyl)ethanimine

Downstream raw materials:

2,2,5,6,6-pentamethyl-hept-4-en-3-one

2,6-dimethylstyrene

Refernces

• 1、 Apeloig, Yitzhak,Franke, Wilfried,Rappoport, Zvi,Schwarz, Helmut,Stahl, Daniel. "Dissociative ionization of aryl-substituted vinyl bromides in the gas phase: Experimental and computational evidence for the formation of stable α-arylvinyl cations both by direct means and spontaneous exothermic isomerization of unstable isomeric ions". . p. 2770 - 2780. Retrieved 2007/10/02.