1-(4-Cyclohexylphenyl)ethanone oxime

Base Information

• Chemical Name: 1-(4-Cyclohexylphenyl)ethanone oxime
• CAS No.: 74067-99-5
• Molecular Formula: C₁₄H₁₉NO
• Molecular Weight: 217.311
• DSSTox Substance ID: DTXSID001290961
• Mol file: 74067-99-5.mol

Synonyms:1-(4-CYCLOHEXYLPHENYL)ETHANONE OXIME;CBDivE_004173;DTXSID001290961;74067-99-5

Chemical Property of 1-(4-Cyclohexylphenyl)ethanone oxime

Chemical Property:

• XLogP3: 4.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 217.146664230
• Heavy Atom Count: 16
• Complexity: 235

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=NO)C1=CC=C(C=C1)C2CCCCC2

Technology Process of 1-(4-Cyclohexylphenyl)ethanone oxime

There total 4 articles about 1-(4-Cyclohexylphenyl)ethanone oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

4-cyclohexylacetophenone (18594-05-3) → ossima del 4-cicloesilacetofenone (74067-99-5)

Guidance literature:

With sodium hydroxide; hydroxylamine hydrochloride; In ethanol; water; for 5h; Heating;

Reference yield:

1-bromocyclohexane (108-85-0) → ossima del 4-cicloesilacetofenone (74067-99-5)

Guidance literature:

Multi-step reaction with 3 steps

1: AlCl₃

2: AlCl₃

3: H₂NOH

With aluminium trichloride; hydroxylamine;

Reference yield:

1-phenyl-1-cyclohexane (827-52-1,5379-26-0) → ossima del 4-cicloesilacetofenone (74067-99-5)

Guidance literature:

Multi-step reaction with 2 steps

1: AlCl₃

2: H₂NOH

With aluminium trichloride; hydroxylamine;

upstream raw materials:

4-cyclohexylacetophenone

1-bromocyclohexane

1-phenyl-1-cyclohexane

benzene

Downstream raw materials:

4-cyclohexylacetophenone

1-[4-(cyclohexyl)-phenyl]ethanone O-(1-naphthylaminocarbonyl)oxime

1-(1-naphthylaminocarbonyloxyimino)-1-(4-cyclohexyl-phenyl)-ethane

C₁₆H₂₁NO

Refernces

• 1、 Byron, D. J.,Matharu, A. S.,Rees, M.,Wilson, R. C.. "Synthesis of Certain Mesogenic Azomethines Derived from 4-Cycloalkylanilines and from 4-Cycloalkylbenzaldehydes". . p. 229 - 238. Retrieved 2007/10/02.
• 2、 De Meglio,Carissimi,Ravenna,Gentili. "New phenylcyclohexyl- and cyclohexylphenylamines. Synthesis and pharmacological activity". . p. 191 - 202. Retrieved 2007/10/02.