2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine

Base Information

• Chemical Name: 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine
• CAS No.: 60188-33-2
• Molecular Formula: C₄₂H₅₀N₄
• Molecular Weight: 610.886
• Mol file: 60188-33-2.mol

Synonyms:2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine

Chemical Property of 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine

Chemical Property:

Purity/Quality:

98.5% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine

There total 12 articles about 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

2,3,7,8,12,13,17,18-octaethyl-porphyrin (2683-82-1,106117-28-6,991-75-3) + phenyllithium (591-51-5) → 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine (60188-33-2)

Guidance literature:

2,3,7,8,12,13,17,18-octaethyl-porphyrin; phenyllithium; In tetrahydrofuran; cyclohexane; at 40 ℃; for 0.25h;

With water; In tetrahydrofuran; cyclohexane;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In tetrahydrofuran; dichloromethane; cyclohexane; for 0.0833333h; Further stages.;

DOI:10.1002/1521-3765(20000804)6:15<2721::AID-CHEM2721>3.0.CO;2-Z

Reference yield: 90.0%

(2,3,7,8,12,13,17,18-Octaethyl-5-phenylporphyrinato)nickel(II) → 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine (60188-33-2)

Guidance literature:

With sulfuric acid; at 20 ℃; for 0.416667h;

DOI:10.1002/1521-3765(20000804)6:15<2721::AID-CHEM2721>3.0.CO;2-Z

Reference yield: 72.0%

2,3,7,8,12,13,17,18-octaethyl-porphyrin (2683-82-1,106117-28-6,991-75-3) + 4-bromo-aniline (106-40-1) → 2,3,7,8,12,13,17,18-octaethyl-5-phenylporphyrine (60188-33-2) + 5-(4-aminophenyl)-2,3,7,8,12,13,17,18-octaethyl-porphyrin

Guidance literature:

4-bromo-aniline; With n-butyllithium; In diethyl ether; hexane; at 0 - 20 ℃; Inert atmosphere;

2,3,7,8,12,13,17,18-octaethyl-porphyrin; In tetrahydrofuran; diethyl ether; hexane; at -40 - 20 ℃; Further stages; Inert atmosphere;

DOI:10.1016/j.tet.2010.03.008

upstream raw materials:

benzaldehyde

2,3,7,8,12,13,17,18-octaethyl-porphyrin

phenyllithium

3,4-diethyl-1H-pyrrole

Downstream raw materials:

2,3,7,8,12,13,17,18-octaethyl-5,15-diphenyl-21H,23H-porphyrin

Refernces

• 1、 Senge, Mathias O.,Kalisch, Werner W.,Bischoff, Ines. "The reaction of porphyrins with organolithium reagents". . p. 2721 - 2738. Retrieved 2000.
• 2、 Senge, Mathias O.,Bischoff, Ines. "SNAr reactions of β-substituted porphyrins and the synthesis of meso substituted tetrabenzoporphyrins". . p. 1647 - 1650. Retrieved 2007/10/03.