Sulfisoxazole diolamine

Base Information

• Chemical Name: Sulfisoxazole diolamine
• CAS No.: 4299-60-9
• Molecular Formula: C11H13N3O3S
• Molecular Weight: 372.4399
• European Community (EC) Number: 224-308-1
• UNII: 30S4B46J8B
• DSSTox Substance ID: DTXSID90195616
• Wikidata: Q27160153
• NCI Thesaurus Code: C66573
• ChEMBL ID: CHEMBL1200321
• Mol file: 4299-60-9.mol

Synonyms:Ammonium Salt Sulfisoxazole;Diolamine, Sulfisoxazole;Gantrisin;Gantrisin Pediatric;Monolithium Salt Sulfisoxazole;Monosodium Salt Sulfisoxazole;Neoxazoi;Pediatric, Gantrisin;Sulfadimethyloxazole;Sulfafurazol FNA;Sulfafurazole;Sulfasoxizole;Sulfisoxazole;Sulfisoxazole Diolamine;Sulfisoxazole, Ammonium Salt;Sulfisoxazole, Monolithium Salt;Sulfisoxazole, Monosodium Salt;Sulfisoxazole, Monosodium, Monomesylate Salt;Sulfisoxazole, Triammonium Salt;TL azole;TL-azole;Triammonium Salt Sulfisoxazole;V Sul;V-Sul

Chemical Property of Sulfisoxazole diolamine

Chemical Property:

• Boiling Point: 482.2oC at 760 mmHg
• Flash Point: 245.4oC
• PSA: 159.09000
• LogP: 2.36090
• Hydrogen Bond Donor Count: 5
• Hydrogen Bond Acceptor Count: 9
• Rotatable Bond Count: 7
• Exact Mass: 372.14674105
• Heavy Atom Count: 25
• Complexity: 402

Purity/Quality:

99% ^*data from raw suppliers

SULFISOXAZOLE DIOLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(ON=C1C)NS(=O)(=O)C2=CC=C(C=C2)N.C(CO)NCCO
• Uses: Antibacterial.
• Clinical Use: 4-Amino-N-(3,5-dimethyl-5-isoxazolyl)benzenesulfonamidecompound with 2,2 -iminobis[ethanol](1:1); 2,2 -iminodiethanol salt of N1-(3,4-dimethyl-5-isoxazolyl)sulfanilamide.This salt is prepared by adding enoughdiethanolamine to a solution of sulfisoxazole to bring thepH to about 7.5. It is used as a salt to make the drug moresoluble in the physiological pH range of 6.0 to 7.5 and isused in solution for systemic administration of the drug byslow intravenous, intramuscular, or subcutaneous injectionwhen high enough blood levels cannot be maintained byoral administration alone. It also is used for instillation ofdrops or ointment in the eye for the local treatment of susceptibleinfections.