Thiepane 1,1-dioxide

Base Information

• Chemical Name: Thiepane 1,1-dioxide
• CAS No.: 6251-33-8
• Molecular Formula: C6H12O2S
• Molecular Weight: 148.226
• Mol file: 6251-33-8.mol

Synonyms:Hexamethylenesulfone;Thiepan-1,1-dioxide;thiepane-1,1-dioxide;Hexamethylene sulfone;hexamethylenesulphone;thiepane 1,1-dioxide;

Chemical Property of Thiepane 1,1-dioxide

Chemical Property:

• Melting Point: 71.2-71.9 °C
• Boiling Point: 127.8±8.0 °C(Predicted)
• PSA: 42.52000
• Density: 1.133±0.06 g/cm3(Predicted)
• LogP: 2.05600

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Thiepane 1,1-dioxide

There total 11 articles about Thiepane 1,1-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

thiepane (4753-80-4) → Hexamethylene sulfone (6251-33-8)

Guidance literature:

With potassium permanganate; N-benzyl-N,N,N-triethylammonium chloride; In dichloromethane; water; for 12h; Ambient temperature;

DOI:10.1021/jo01306a019

Reference yield:

thiepane (4753-80-4) → Hexamethylene sulfone (6251-33-8) + 1-thiacycloheptane 1-oxide (6251-34-9)

Guidance literature:

With oxygen; 5,10,15,20-tetrakisphenylporphyrin; In tetrahydrofuran; at -39 ℃; for 1h; pyrex, 500 W halogen lamp;

DOI:10.1016/S0040-4039(00)98765-3

Reference yield:

hex-5-ene-1-sulfonyl chloride (133216-86-1) → Hexamethylene sulfone (6251-33-8)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene; at 50 ℃; for 11h;

upstream raw materials:

thiepane

1 ,6-dibromohexane

hex-5-ene-1-sulfonyl chloride

6-Bromo-1-hexene

Downstream raw materials:

tridecafluorohexanesulfonyl fluoride

Refernces

• 1、 Clennan, Edward L.,Zhou, Wenhui,Chan, Jacqueline. "Mechanistic organic chemistry in a microreactor. Zeolite-controlled photooxidations of organic sulfides". . p. 9368 - 9378. Retrieved 2007/10/03.
• 2、 Culshaw,Walton. "Regioselectivity in the formation of cyclic sulphones from 4- and 5-alkenesulphonyl chlorides". . p. 6433 - 6436. Retrieved 2007/10/02.