Acid red 52

Base Information

• Chemical Name: Acid red 52
• CAS No.: 3520-42-1
• Deprecated CAS: 103947-10-0,104298-69-3,12777-86-5,184827-20-1,192230-72-1,204996-41-8,39470-83-2,61261-16-3,74871-35-5,288323-20-6,475472-70-9,1107507-72-1,1108610-30-5,104298-69-3,1107507-72-1,1108610-30-5,12777-86-5,184827-20-1,204996-41-8,288323-20-6,39470-83-2,475472-70-9,61261-16-3,74871-35-5
• Molecular Formula: C27H29N2O7S2^.Na
• Molecular Weight: 580.658
• Hs Code.: 32129000
• European Community (EC) Number: 222-529-8
• UNII: 821LWZ3R6R
• DSSTox Substance ID: DTXSID7021235
• Wikipedia: Sulforhodamine_B
• ChEMBL ID: CHEMBL1306565
• Mol file: 3520-42-1.mol

Synonyms:Acid Red;acid red, isoxanthene;C.I. 45100;C.I. acid red 52;caries check;erio acid red;kiton red S;lissamine rhodamine B;lissamine rhodamine B, sodium salt;R-106;sulforhodamine B;sulforodamine B;sulphorhodamine B

Chemical Property of Acid red 52

Chemical Property:

• Appearance/Colour: Deep red powder
• PSA: 150.78000
• Density: 1.472[at 20℃]
• LogP: 7.81310
• Storage Temp.: room temp
• Solubility.: methanol: 1 mg/mL
• Water Solubility.: 95.3g/L at 20℃
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 8
• Rotatable Bond Count: 6
• Exact Mass: 580.13138790
• Heavy Atom Count: 39
• Complexity: 1150

Purity/Quality:

98%min ^*data from raw suppliers

Sulforhodamine B sodium salt ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 22-24/25-26-36/37/39

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Dyes -> Di- and Triaryl Dyes
• Canonical SMILES: CCN(CC)C1=CC2=C(C=C1)C(=C3C=CC(=[N+](CC)CC)C=C3O2)C4=C(C=C(C=C4)S(=O)(=O)[O-])S(=O)(=O)[O-].[Na+]
• Uses: Sulforhodamine B Sodium Salt is a rhodamine dye widely used in nonpermanent tattoos. Studies show that Sulforhodamine B can be used as a potential new therapeutic agent for the treatment of the acute respiratory distress syndrome. Dyes and metabolites, Environmental Testing Sulforhodamine B sodium salt has been used:for relative total cell mass quantificationto investigate the viscosity of coacervatesas a molecular rotor for microviscosity determination in aerosol droplets Sulforhodamine B (SRB) is known for use in SRB assay for the determination of in vitro cytotoxicity through staining and the observation of live cells, proliferation and drug screening.It has been used in the SRB assay to evaluate the effect of mouthwashes on protein content in primary cultures of human fibroblasts.It is also suitable as a microscopic tracer for the assessment of blood-brain barrier integrity by post mortem inspection of frozen sections. SRB is useful as a caries detector dye with subsequent inspection of histological material.

Technology Process of Acid red 52

There total 1 articles about Acid red 52 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ sulforhodamine B (3520-42-1)

Guidance literature:

Reference yield: 88.0%

sulforhodamine B (3520-42-1) → rhodamine B sulfonyl chloride (62796-29-6)

Guidance literature:

With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 20 ℃; for 16h;

DOI:10.1055/s-2008-1032172

Reference yield: 76.0%

1-amino-2-azidoethane (87156-40-9) + sulforhodamine B (3520-42-1) → C29H34N6O6S2

Guidance literature:

With triethylamine; In N,N-dimethyl-formamide; at 20 ℃; Darkness;

DOI:10.1021/acs.orglett.7b02464

Downstream raw materials:

rhodamine B sulfonyl chloride

Refernces

• 1、 -. "Oligonucleotides comprising a molecular switch". . . Retrieved 2008/06/13.
• 2、 -. "Dual resonance energy transfer nucleic acid probes". . . Retrieved 2008/06/13.