GA₃-7-alkohol

Base Information

• Chemical Name: GA₃-7-alkohol
• CAS No.: 54878-53-4
• Molecular Formula: C₁₉H₂₄O₅
• Molecular Weight: 332.397
• Mol file: 54878-53-4.mol

Synonyms:GA₃-7-alkohol

Chemical Property of GA₃-7-alkohol

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of GA₃-7-alkohol

There total 2 articles about GA₃-7-alkohol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

2β,4a,7-trihydroxy-1-methyl-8-methylene-gibb-3-ene-1α,10β-dicarboxylic acid 10,10'-anhydride 1->4a;1'->4'a-dilactone (19123-33-2) → GA3-7-alkohol (54878-53-4) + (3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno[1,2-b]furan-4-carboxylic acid (77-06-5)

Guidance literature:

With sodium tetrahydroborate; acetic acid; In tetrahydrofuran; for 0.5h; Yield given;

DOI:10.1016/0040-4020(80)87025-6

Reference yield: 3.0%

(3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno[1,2-b]furan-4-carboxylic acid (77-06-5) → GA3-7-alkohol (54878-53-4) + C32H44N2O6 (58870-20-5)

Guidance literature:

With sodium tetrahydroborate; dicyclohexyl-carbodiimide; In tetrahydrofuran; 1,4-dioxane; 1.) -15 deg C, 2.) 5 deg C, 12 h;

DOI:10.1016/0040-4020(80)87025-6

upstream raw materials:

2β,4a,7-trihydroxy-1-methyl-8-methylene-gibb-3-ene-1α,10β-dicarboxylic acid 10,10'-anhydride 1->4a;1'->4'a-dilactone

(3S,3aS,4S,4aS,6S,8aR,8bR,11S)-6,11-dihydroxy-3-methyl-12-methylene-2-oxo-4a,6-ethano-3,8b-prop-1-enoperhydroindeno[1,2-b]furan-4-carboxylic acid

Refernces