2,3-Pyridinedicarboximide

Base Information

• Chemical Name: 2,3-Pyridinedicarboximide
• CAS No.: 4664-00-0
• Molecular Formula: C7H4N2O2
• Molecular Weight: 148.121
• Hs Code.: 2933990090
• European Community (EC) Number: 225-107-1
• NSC Number: 405554
• UNII: EL02DAU9PG
• DSSTox Substance ID: DTXSID40196890
• Nikkaji Number: J85.644D
• Wikidata: Q27894174
• Mol file: 4664-00-0.mol

Synonyms:2,3-PyDCA;2,3-pyridinedicarboximide

Chemical Property of 2,3-Pyridinedicarboximide

Chemical Property:

• Appearance/Colour: Light yellow solid
• Melting Point: 233-234 °C
• Refractive Index: 1.622
• Boiling Point: 268.69°C (rough estimate)
• PKA: 8.08±0.20(Predicted)
• PSA: 59.06000
• Density: 1.47 g/cm³
• LogP: 0.29400
• Storage Temp.: Refrigerator
• Solubility.: Dichloromethane, Ether, Ethyl Acetate, Methanol
• XLogP3: 0
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 148.027277375
• Heavy Atom Count: 11
• Complexity: 215

Purity/Quality:

98%,99%, ^*data from raw suppliers

Quinolinimide ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C(=O)NC2=O)N=C1
• Uses: Quinolinimide (cas# 4664-00-0) is a compound useful in organic synthesis.

Technology Process of 2,3-Pyridinedicarboximide

There total 14 articles about 2,3-Pyridinedicarboximide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Pyridine-2,3-dicarboxylic anhydride (699-98-9) → 2,3-pyridinedicarboximide (4664-00-0,303983-78-0)

Guidance literature:

With acetamide; at 165 ℃; for 2.5h;

DOI:10.1016/j.tet.2010.03.100

Reference yield: 84.0%

Pyridine-2,3-dicarboxylic acid (89-00-9) → 2,3-pyridinedicarboximide (4664-00-0,303983-78-0)

Guidance literature:

With ammonium hydroxide; at 140 ℃; for 6h; Reagent/catalyst;

Reference yield: 66.0%

Pyridine-2,3-dicarboxylic anhydride (699-98-9) + Pyridine-2,3-dicarboxylic acid (89-00-9) → 2,3-pyridinedicarboximide (4664-00-0,303983-78-0)

Guidance literature:

Pyridine-2,3-dicarboxylic acid; With acetic anhydride; Reflux;

Pyridine-2,3-dicarboxylic anhydride; With acetamide; acetic anhydride;

upstream raw materials:

acetamide

Pyridine-2,3-dicarboxylic anhydride

urea

2-cyanopyridine-3-carboxylic acid

Downstream raw materials:

7H-furo[3,4-b]pyridin-5-one

pyridine-2,3-dicarboxamide

3-amino-pyridine-2-carboxylic acid

6,7-Dihydro-7-hydroxy-5H-pyrrolo<3,4-b>pyridin-5-one

Refernces

• 1、 -. "Method for preparing 6-(1-phenyl-ethyl)-pyrrolo[3,4-b]pyridine-5,7-dione". Paragraph 0016. . Retrieved 2017/05/26.
• 2、 Zhang, Lei,Yuan, Jun,Xu, Yufang,Zhang, Y.-H. Percival,Qian, Xuhong. "New artificial fluoro-cofactor of hydride transfer with novel fluorescence assay for redox biocatalysis". supporting information. p. 6471 - 6474. Retrieved 2016/06/06.