methyl 2-benzoyl-4,5-dimethylbenzoate

Base Information

• Chemical Name: methyl 2-benzoyl-4,5-dimethylbenzoate
• CAS No.: 412322-32-8
• Molecular Formula: C₁₇H₁₆O₃
• Molecular Weight: 268.312
• Mol file: 412322-32-8.mol

Synonyms:methyl 2-benzoyl-4,5-dimethylbenzoate

Chemical Property of methyl 2-benzoyl-4,5-dimethylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 2-benzoyl-4,5-dimethylbenzoate

There total 5 articles about methyl 2-benzoyl-4,5-dimethylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

methyl 4-oxo-4-phenylbut-2-ynoate (41158-32-1) + 2,3-dimethyl-buta-1,3-diene (513-81-5) → methyl 2-benzoyl-4,5-dimethylbenzoate (412322-32-8)

Guidance literature:

methyl 4-oxo-4-phenylbut-2-ynoate; 2,3-dimethyl-buta-1,3-diene; With zinc(II) iodide; In dichloromethane; at 20 ℃; for 16h; Inert atmosphere;

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In toluene; at 20 ℃; for 2.5h; Inert atmosphere;

DOI:10.1021/ol4023276

Reference yield:

Benzoylacrylic acid (17812-07-6) → methyl 2-benzoyl-4,5-dimethylbenzoate (412322-32-8)

Guidance literature:

Multi-step reaction with 2 steps

1: ethanol / 105 °C

2: sulfuric acid / Erhitzen des Reaktionsprodukts mit Schwefel auf 245grad

With ethanol; sulfuric acid;

DOI:10.1021/ja01312a054

Reference yield:

benzene (71-43-2,26181-88-4,54682-86-9,13967-78-7,174973-66-1) → methyl 2-benzoyl-4,5-dimethylbenzoate (412322-32-8)

Guidance literature:

Multi-step reaction with 3 steps

1: aluminium chloride

2: ethanol / 105 °C

3: sulfuric acid / Erhitzen des Reaktionsprodukts mit Schwefel auf 245grad

With aluminium trichloride; ethanol; sulfuric acid;

DOI:10.1021/ja01312a054

upstream raw materials:

methanol

(+/-)-3.4-dimethyl-6t-benzoyl-cyclohexene-⁽³⁾-carboxylic acid-(1r)

Benzoylacrylic acid

benzene

Downstream raw materials:

2,3-dimethylanthraquinone

2-benzoyl-4,5-dimethylbenzoic acid

Refernces