Technology Process of 3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-2-deoxy-1-O-hexadecyl-2-hexanamido-sn-glycerol
There total 8 articles about 3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-2-deoxy-1-O-hexadecyl-2-hexanamido-sn-glycerol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
4 A molecular sieve; triphenylphosphine;
In
benzene;
for 48h;
DOI:10.1021/ja020396+
- Guidance literature:
-
Multi-step reaction with 6 steps
1: 79 percent / triethylamine; (dimethylamino)pyridine / CH2Cl2 / 18 h / 20 °C
2: 85 percent / pyridine / 0 - 20 °C
3: 88 percent / sodium azide / dimethylformamide / 14 h / 100 °C
4: 88 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1.5 h / 20 °C
5: 61 percent / (trimethylsilyl)trifluoromethane sulfonate; molecular sieves 4A / CH2Cl2 / 0 °C
6: 49 percent / triphenylphosphine; molecular sieves 4A / benzene / 48 h
With
pyridine; dmap; sodium azide; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; tetrabutyl ammonium fluoride; triethylamine; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja020396+
- Guidance literature:
-
Multi-step reaction with 5 steps
1: 85 percent / pyridine / 0 - 20 °C
2: 88 percent / sodium azide / dimethylformamide / 14 h / 100 °C
3: 88 percent / tetrabutylammonium fluoride / tetrahydrofuran / 1.5 h / 20 °C
4: 61 percent / (trimethylsilyl)trifluoromethane sulfonate; molecular sieves 4A / CH2Cl2 / 0 °C
5: 49 percent / triphenylphosphine; molecular sieves 4A / benzene / 48 h
With
pyridine; sodium azide; trimethylsilyl trifluoromethanesulfonate; 4 A molecular sieve; tetrabutyl ammonium fluoride; triphenylphosphine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; benzene;
DOI:10.1021/ja020396+