Potasan

Base Information

• Chemical Name: Potasan
• CAS No.: 299-45-6
• Molecular Formula: C14H17 O5 P S
• Molecular Weight: 328.326
• UNII: S270N91705
• DSSTox Substance ID: DTXSID70871628
• Nikkaji Number: J5.469K
• Wikidata: Q15632901
• Mol file: 299-45-6.mol

Synonyms:hymecromone O,O-diethyl phosphorothioate;O,O-diethyl O-(4-methyl-7-coumarinyl) phosphorothioate;Potasan

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of Potasan

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Melting Point: 39.5-41.3°
• Refractive Index: nD37 1.5685 (liq)
• Boiling Point: 425.3°Cat760mmHg
• Flash Point: 211°C
• PSA: 99.80000
• Density: 1.295g/cm³
• LogP: 4.42830
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 6
• Exact Mass: 328.05343181
• Heavy Atom Count: 21
• Complexity: 454

Purity/Quality:

Safty Information:

• Pictogram(s): Toxic by ingestion, cholinesterase inhibitor.
• Hazard Codes: T+,N
• Statements: 26/27/28-50/53
• Safety Statements: 13-28-45-60-61

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOP(=S)(OCC)OC1=CC2=C(C=C1)C(=CC(=O)O2)C
• Uses: Systemic insecticide, especially effective against the Colorado beetle.

Technology Process of Potasan

There total 3 articles about Potasan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

sodium 4-methylumbelliferonate (5980-33-6) + diethyl phosphorochloridothioate (2524-04-1) → potasan (299-45-6)

Guidance literature:

In N,N-dimethyl-formamide;

Reference yield: 52.0%

7-hydroxy-4-methyl-chromen-2-one (90-33-5,79566-13-5) + diethyl phosphorochloridothioate (2524-04-1) → potasan (299-45-6)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 0 - 5 ℃; for 12h;

DOI:10.1016/j.jfluchem.2006.07.017

Reference yield:

→ potasan (299-45-6)

Guidance literature:

upstream raw materials:

7-hydroxy-4-methyl-chromen-2-one

diethyl phosphorochloridothioate

sodium 4-methylumbelliferonate

Downstream raw materials:

4-methyl-7-ethoxycoumarin

O,O-diethyl-O-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-phosphate

Refernces

• 1、 Chavan, Vishal P.,Mane, Avinash S.,Shingare, Murlidhar S.. "Synthesis of new O,O -dialkyl-O-coumarinophosphorothioates and their pesticidal bioassay against Helicoverpa armigera". . p. 339 - 341. Retrieved 2007/10/03.
• 2、 -. "Condensation products". . . Retrieved 2008/06/13.