estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate

Base Information

• Chemical Name: estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate
• CAS No.: 15140-27-9
• Molecular Formula: C25H34O3
• Molecular Weight: 382.543
• Mol file: 15140-27-9.mol

Synonyms:Estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate;

Chemical Property of estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate

Chemical Property:

• Vapor Pressure: 1.54E-11mmHg at 25°C
• Melting Point: 174℃
• Refractive Index: 1.584
• Boiling Point: 522.6 °C at 760 mmHg
• PKA: 10.25±0.60(Predicted)
• Flash Point: 205.4 °C
• PSA: 46.53000
• Density: 1.16 g/cm³
• LogP: 5.74040
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate

There total 2 articles about estra-1,3,5(10)-triene-3,17beta-diol 17-cyclohexanecarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3,17β-bis-cyclohexanecarbonyloxy-estra-1,3,5(10)-triene (90462-43-4) → 17β-cyclohexanecarbonyloxy-estra-1,3,5(10)-trien-3-ol (15140-27-9)

Guidance literature:

With sodium hydroxide;

Reference yield:

estradiol (50-28-2) → 17β-cyclohexanecarbonyloxy-estra-1,3,5(10)-trien-3-ol (15140-27-9)

Guidance literature:

Multi-step reaction with 2 steps

1: pyridine

2: aqueous NH₃

With pyridine; ammonium hydroxide;

upstream raw materials:

3,17β-bis-cyclohexanecarbonyloxy-estra-1,3,5(10)-triene

estradiol