Medifoxamine

Base Information

• Chemical Name: Medifoxamine
• CAS No.: 32359-34-5
• Molecular Formula: C16H19NO2
• Molecular Weight: 257.332
• Hs Code.: 2922299090
• European Community (EC) Number: 251-011-4
• UNII: KWU7C2A1NT
• DSSTox Substance ID: DTXSID80186078
• Nikkaji Number: J19.959A
• Wikipedia: Medifoxamine
• Wikidata: Q544834
• NCI Thesaurus Code: C83914
• Metabolomics Workbench ID: 154049
• ChEMBL ID: CHEMBL85231
• Mol file: 32359-34-5.mol

Synonyms:medifoxamine;medifoxamine fumarate

Chemical Property of Medifoxamine

Chemical Property:

• Melting Point: 138 °C
• Boiling Point: 379.968 °C at 760 mmHg
• PKA: 7.39±0.28(Predicted)
• Flash Point: 132.866 °C
• PSA: 21.70000
• Density: 1.077 g/cm³
• LogP: 3.03210
• XLogP3: 3.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 6
• Exact Mass: 257.141578849
• Heavy Atom Count: 19
• Complexity: 213

Purity/Quality:

98%Min ^*data from raw suppliers

MEDIFOXAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC(OC1=CC=CC=C1)OC2=CC=CC=C2
• Description: Medifoxamine fumarate is reported to be an imipramine-like antidepressant with anxiolytic, antispasmodic, and antiserotonin properties. It is devoid of anticholinergic activity.

Technology Process of Medifoxamine

There total 2 articles about Medifoxamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

diphenoxy-acetic acid dimethylamide (1033-99-4) → 2,2-Bisphenoxy-dimethyl-aminoethane (32359-34-5)

Guidance literature:

With lithium aluminium tetrahydride;

Reference yield:

→ 2,2-Bisphenoxy-dimethyl-aminoethane (32359-34-5)

Guidance literature:

N,N-Dimethyldiphenoxyacetamid, LiAlH4-Red.;

upstream raw materials:

diphenoxy-acetic acid dimethylamide