Technology Process of 17-Bromoheptadecanoic acid
There total 15 articles about 17-Bromoheptadecanoic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
benzyl 17-((methylsulfonyl)oxy)heptadec-5-enoate;
With
triethylsilane; palladium(II) hydroxide;
In
methanol; dichloromethane;
at 20 ℃;
With
tetra(n-butyl)ammonium hydrogensulfate; potassium bromide;
In
water; toluene;
at 100 ℃;
for 4h;
DOI:10.1016/j.bmc.2016.06.007
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 2 h / 0 - 20 °C / Inert atmosphere
2.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C / Inert atmosphere
3.1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / -78 - 20 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C
5.1: pyridine / tetrahydrofuran / 0 - 20 °C
6.1: triethylsilane; palladium(II) hydroxide / dichloromethane; methanol / 20 °C
6.2: 4 h / 100 °C
With
pyridine; triethylsilane; tetrabutyl ammonium fluoride; palladium(II) hydroxide; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; lithium hexamethyldisilazane; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane; toluene;
DOI:10.1016/j.bmc.2016.06.007
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: 1H-imidazole / tetrahydrofuran; N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C
2.1: triphenylphosphine; diethylazodicarboxylate / tetrahydrofuran; toluene / 2 h / 0 - 20 °C / Inert atmosphere
3.1: 3-chloro-benzenecarboperoxoic acid / dichloromethane / 0 - 20 °C / Inert atmosphere
4.1: lithium hexamethyldisilazane / tetrahydrofuran / 3 h / -78 - 20 °C / Inert atmosphere
5.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0 - 20 °C
6.1: pyridine / tetrahydrofuran / 0 - 20 °C
7.1: triethylsilane; palladium(II) hydroxide / dichloromethane; methanol / 20 °C
7.2: 4 h / 100 °C
With
pyridine; 1H-imidazole; triethylsilane; tetrabutyl ammonium fluoride; palladium(II) hydroxide; 3-chloro-benzenecarboperoxoic acid; triphenylphosphine; lithium hexamethyldisilazane; diethylazodicarboxylate;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.bmc.2016.06.007
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