4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate

Base Information

• Chemical Name: 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate
• CAS No.: 1403747-89-6
• Molecular Formula: C₂F₃O₂*C₁₁H₂₀N₃O
• Molecular Weight: 323.315
• Mol file: 1403747-89-6.mol

Synonyms:4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate

Chemical Property of 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate

There total 3 articles about 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium bromide (1403747-72-7) + lead(II) trifluoroacetate (4146-73-0,16656-82-9,135179-18-9) → 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate (1403747-89-6)

Guidance literature:

In water; at 0 ℃;

DOI:10.3998/ark.5550190.0013.823

Reference yield:

trans-2-(1H-1,2,4-triazol-1-yl)cyclohexanol → 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate (1403747-89-6)

Guidance literature:

Multi-step reaction with 3 steps

1: Amano PS-C lipase / tert-Amyl alcohol / 33 h / 20 °C

2: 96 h / 65 °C

3: water / 0 °C

With Amano PS-C lipase; In tert-Amyl alcohol; water;

DOI:10.3998/ark.5550190.0013.823

Reference yield:

cyclohexane-1,2-epoxide (286-20-4) → 4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium trifluoroacetate (1403747-89-6)

Guidance literature:

Multi-step reaction with 4 steps

1: neat (no solvent) / 72 h / 65 °C

2: Amano PS-C lipase / tert-Amyl alcohol / 33 h / 20 °C

3: 96 h / 65 °C

4: water / 0 °C

With Amano PS-C lipase; In tert-Amyl alcohol; water;

DOI:10.3998/ark.5550190.0013.823

upstream raw materials:

4-propyl-1-[(1S,2S)-2-hydroxycyclohexyl]-1H-1,2,4-triazol-4-ium bromide

lead(II) trifluoroacetate

cyclohexane-1,2-epoxide

Refernces