2--4--L-2,4-diaminobutyric amide

Base Information

• Chemical Name: 2--4--L-2,4-diaminobutyric amide
• CAS No.: 244185-29-3
• Molecular Formula: C₁₇H₂₅N₃O₅
• Molecular Weight: 351.403
• Mol file: 244185-29-3.mol

Synonyms:2--4--L-2,4-diaminobutyric amide

Chemical Property of 2--4--L-2,4-diaminobutyric amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2--4--L-2,4-diaminobutyric amide

There total 7 articles about 2--4--L-2,4-diaminobutyric amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

2--4--L-2,4-diaminobutyric acid (49855-91-6) → 2--4--L-2,4-diaminobutyric amide (244185-29-3)

Guidance literature:

2--4--L-2,4-diaminobutyric acid; With 4-methyl-morpholine; isobutyl chloroformate; In tetrahydrofuran; at 0 - 20 ℃;

With ammonia; In tetrahydrofuran; methanol; at 0 - 20 ℃; for 3.08333h;

Reference yield: 40.0%

2--4--L-2,4-diaminobutyric acid (49855-91-6) + isobutyl chloroformate (543-27-1) → 2--4--L-2,4-diaminobutyric amide (244185-29-3)

Guidance literature:

2--4--L-2,4-diaminobutyric acid; isobutyl chloroformate; With 4-methyl-morpholine; In tetrahydrofuran; at 0 - 20 ℃; for 17h;

With ammonia; In methanol; at 0 - 20 ℃; for 3.08333h;

Reference yield: 40.0%

2--4--L-2,4-diaminobutyric p-nitrophenyl ester (125156-36-7) → 2--4--L-2,4-diaminobutyric amide (244185-29-3)

Guidance literature:

With ammonia; In tetrahydrofuran; for 1h;

DOI:10.1021/jm990111c

upstream raw materials:

2--4--L-2,4-diaminobutyric p-nitrophenyl ester

di-tert-butyl dicarbonate

2--4--L-2,4-diaminobutyric acid

benzyl chloroformate

Downstream raw materials:

tert-butyl N-[(3S)-3-amino-3-carbamoyl propyl]carbamate

Refernces

• 1、 -. "BENZODIAZOLIUM COMPOUNDS AS ENAC INHIBITORS". Page/Page column 158. . Retrieved 2018/06/12.