(Z)-N'-benzylidenebenzohydrazide

Base Information

• Chemical Name: (Z)-N'-benzylidenebenzohydrazide
• CAS No.: 14850-88-5
• Molecular Formula: C₁₄H₁₂N₂O
• Molecular Weight: 224.262
• Mol file: 14850-88-5.mol

Synonyms:(Z)-N'-benzylidenebenzohydrazide

Chemical Property of (Z)-N'-benzylidenebenzohydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (Z)-N'-benzylidenebenzohydrazide

There total 54 articles about (Z)-N'-benzylidenebenzohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

benzaldehyde (100-52-7) + benzoic acid hydrazide (613-94-5) → benzoylhydrazone of benzaldehyde (14850-88-5,14850-89-6,956-07-0)

Guidance literature:

In ethanol; for 6h; Heating;

Reference yield: 85.0%

1-methyl-3,5-bis(phenylmethylidene)piperidin-4-one hydrochloride (54237-25-1) + benzoic acid hydrazide (613-94-5) → benzoylhydrazone of benzaldehyde (14850-88-5,14850-89-6,956-07-0)

Guidance literature:

In dichloromethane; at 80 ℃; for 24h;

DOI:10.1002/jhet.1570

Reference yield: 58.0%

benzoylformic acid (N-benzoyl)hydrazone (5199-89-3) → diphenyl-[1,3,4]thiadiazole (1456-21-9) + benzoylhydrazone of benzaldehyde (14850-88-5,14850-89-6,956-07-0)

Guidance literature:

With sulfur; In benzene; for 14h; Heating;

DOI:10.1016/S0040-4020(01)86099-3

upstream raw materials:

benzaldehyde, hydrazone

benzoic acid ethyl ester

bis-benzoylmercapto-phenyl-methane

N'-benzylidene-benzohydrazonoyl azide

Downstream raw materials:

1,4-diphenyl-1-ethylxanthyl-2,3-diazabutadiene

(E)-N'-benzylidenebenzohydrazide

N-(3-Chloro-2-oxo-4-phenyl-azetidin-1-yl)-benzamide

benzaldehyde N-methyl-N-benzoylhydrazone

Refernces

• 1、 Buss, Joan L.,Neuzil, Jiri,Gellert, Nina,Weber, Christian,Ponka, Prem. "Pyridoxal isonicotinoyl hydrazone analogs induce apoptosis in hematopoietic cells due to their iron-chelating properties". . p. 161 - 172. Retrieved 2003.
• 2、 -. "Analogs of Nitrofuran Antibiotics to Combat Resistance". Paragraph 0125; 0162; 0194; 0196. . Retrieved 2022/01/24.
• 3、 Chapman, Eli,Chitre, Siddhi,Hoang, Quyen Q.,Howe, Chris,Johnson, Steven M.,Park, Yangshin,Ray, Anne-Marie,Sivinski, Jared,Stevens, Mckayla,Washburn, Alex. "Analogs of nitrofuran antibiotics are potent GroEL/ES inhibitor pro-drugs". . . Retrieved 2020/09/15.