octa-O-acetylhesperidin

Base Information

• Chemical Name: octa-O-acetylhesperidin
• CAS No.: 25227-16-1
• Molecular Formula: C₄₄H₅₀O₂₃
• Molecular Weight: 946.867
• Mol file: 25227-16-1.mol

Synonyms:octa-O-acetylhesperidin

Chemical Property of octa-O-acetylhesperidin

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of octa-O-acetylhesperidin

There total 2 articles about octa-O-acetylhesperidin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

acetic anhydride (108-24-7) + hesperidin (520-26-3) → octa-O-acetylhesperidin (25227-16-1)

Guidance literature:

With dmap; In N,N-dimethyl-formamide; at 45 ℃; for 1h;

DOI:10.1080/14786419.2022.2031186

Reference yield:

→ Acetylhesperidin (25227-16-1)

Guidance literature:

Hesperidin, Ac2O/Eg.;

Reference yield: 59.0%

Acetic acid 2-(3-acetoxy-4-methoxy-phenyl)-4-oxo-7-[(3R,4S,5R,6R)-3,4,5-triacetoxy-6-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-2-yloxy]-chroman-5-yl ester (25227-16-1) → Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-2-{4-[3-(3-acetoxy-4-methoxy-phenyl)-propyl]-3,5-dihydroxy-phenoxy}-6-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-3-yl ester (128373-99-9) + Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-2-{3-acetoxy-4-[3-(3-acetoxy-4-methoxy-phenyl)-propyl]-5-hydroxy-phenoxy}-6-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-3-yl ester (128374-00-5)

Guidance literature:

With sodium cyanoborohydride; In trifluoroacetic acid; 1) in ice-bath, 2) room temp., 1 h;

DOI:10.1016/S0040-4039(01)93420-3

upstream raw materials:

acetic anhydride

hesperidin

Downstream raw materials:

Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-2-{4-[3-(3-acetoxy-4-methoxy-phenyl)-propyl]-3,5-dihydroxy-phenoxy}-6-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-3-yl ester

Acetic acid (3R,4S,5R,6R)-4,5-diacetoxy-2-{3-acetoxy-4-[3-(3-acetoxy-4-methoxy-phenyl)-propyl]-5-hydroxy-phenoxy}-6-((2S,3R,4R,5S,6S)-3,4,5-triacetoxy-6-methyl-tetrahydro-pyran-2-yloxymethyl)-tetrahydro-pyran-3-yl ester

Refernces

• 1、 Kubo, Masayoshi,Sasaki, Hiroshi,Endo, Tohru,Taguchi, Heihachiro,Yosioka, Itiro. "The Constituents of Schizonepeta tenuifolia BRIQ. II. Structure of a New Monoterpene Glucoside, Schizonepetoside C". . p. 3097 - 3101. Retrieved 2007/10/02.