3-phenoxypropionyl hydrazide hydrochloride

Base Information

• Chemical Name: 3-phenoxypropionyl hydrazide hydrochloride
• CAS No.: 103965-96-4
• Molecular Formula: C₉H₁₂N₂O₂*ClH
• Molecular Weight: 216.667
• Mol file: 103965-96-4.mol

Synonyms:3-phenoxypropionyl hydrazide hydrochloride

Chemical Property of 3-phenoxypropionyl hydrazide hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-phenoxypropionyl hydrazide hydrochloride

There total 1 articles about 3-phenoxypropionyl hydrazide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 3-phenoxypropionyl hydrazide hydrochloride (103965-96-4)

Guidance literature:

Reference yield:

3-phenoxypropionyl hydrazide hydrochloride (103965-96-4) → nefazadone (83366-66-9)

Guidance literature:

Multi-step reaction with 4 steps

1: 1) NaNO₂, aq.HCl / 1) water, toluene, ice- bath, 20 min, 2) toluene, steam bath

2: toluene / 0.25 h / ice bath

3: 64 percent / KOH / H₂O / 0.67 h / 95 - 96 °C

4: 84 percent / 50percent aq. NaOH / propan-2-ol / 7 h / Heating

With hydrogenchloride; potassium hydroxide; sodium hydroxide; sodium nitrite; In water; isopropyl alcohol; toluene;

DOI:10.1002/jhet.5570220440

Reference yield:

3-phenoxypropionyl hydrazide hydrochloride (103965-96-4) → 5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one (95885-13-5)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) NaNO₂, aq.HCl / 1) water, toluene, ice- bath, 20 min, 2) toluene, steam bath

2: toluene / 0.25 h / ice bath

3: 64 percent / KOH / H₂O / 0.67 h / 95 - 96 °C

With hydrogenchloride; potassium hydroxide; sodium nitrite; In water; toluene;

DOI:10.1002/jhet.5570220440

Downstream raw materials:

2-phenoxyethylisocyanate

5-ethyl-4-(2-phenoxyethyl)-2H-1,2,4-triazol-3(4H)-one

1-propionyl-4-(2-phenoxyethyl)semicarbazide

nefazadone

Refernces

• 1、 -. "1,2,4-TRIAZOL-3-ONE ANTIDEPRESSANTS". . . Retrieved 2008/06/13.