2-Chloroethyl 4-chlorophenyl sulfone

Base Information

• Chemical Name: 2-Chloroethyl 4-chlorophenyl sulfone
• CAS No.: 16191-84-7
• Molecular Formula: C8H8 Cl2 O2 S
• Molecular Weight: 239.122
• European Community (EC) Number: 240-323-6
• NSC Number: 196185
• UNII: 77XFY6CPD8
• DSSTox Substance ID: DTXSID70167275
• Nikkaji Number: J15.575F
• Wikidata: Q83036612
• Mol file: 16191-84-7.mol

Synonyms:16191-84-7;2-Chloroethyl 4-chlorophenyl sulfone;1-Chloro-4-((2-chloroethyl)sulfonyl)benzene;1-chloro-4-(2-chloroethylsulfonyl)benzene;SULFONE, 2-CHLOROETHYL p-CHLOROPHENYL;p-Chlorophenyl 2-chloroethyl sulfone;1-Chloro-4-[(2-chloroethyl)sulfonyl]benzene;EINECS 240-323-6;Benzene, 1-chloro-4-((2-chloroethyl)sulfonyl)-;NSC 196185;BRN 2269628;1-Chloro-4-((2-chloroethyl)sulphonyl)benzene;Benzene, 1-chloro-4-[(2-chloroethyl)sulfonyl]-;2-Chloroethyl (4-chlorophenyl)sulfone;NSC-196185;1-chloro-4-[(2-chloroethyl)sulphonyl]benzene;2-CHLOROETHYL-P-CHLOROPHENYL SULFONE;2-Chloroethyl4-chlorophenylsulfone;WLN: G2SWR DG;77XFY6CPD8;SCHEMBL426162;KXQHTLXSDBXWNB-UHFFFAOYSA-;DTXSID70167275;2-Chloroethyl p-chlorophenyl sulfone;MFCD00018966;NSC196185;AKOS001060833;p-Chlorophenyl-beta-chloroethyl sulfone;LS-147987;CS-0318468;FT-0637335;D89388;1-Chloro-4-[(2-chloroethyl)sulfonyl]benzene #;A883045;Z55993085

Chemical Property of 2-Chloroethyl 4-chlorophenyl sulfone

Chemical Property:

• Vapor Pressure: 9.48E-06mmHg at 25°C
• Melting Point: 96°C
• Boiling Point: 383.8°Cat760mmHg
• Flash Point: 185.9°C
• PSA: 42.52000
• Density: 1.397g/cm³
• LogP: 3.43330
• Storage Temp.: Sealed in dry,Room Temperature
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 237.9622061
• Heavy Atom Count: 13
• Complexity: 237

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-Chloroethyl 4-Chlorophenyl Sulfone ^*data from reagent suppliers

Safty Information:

• Safety Statements: 22-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=CC=C1S(=O)(=O)CCCl)Cl

Technology Process of 2-Chloroethyl 4-chlorophenyl sulfone

There total 6 articles about 2-Chloroethyl 4-chlorophenyl sulfone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

2-chloroethyl 4-chlorophenyl sulfide (14366-73-5) → 2-chloro-1-[(4-chlorophenyl)sulfonyl]ethane (16191-84-7)

Guidance literature:

With dihydrogen peroxide; In acetic acid;

Reference yield: 87.5%

2-[(4-chlorophenyl)sulfonyl]ethanol (35847-95-1) → 2-chloro-1-[(4-chlorophenyl)sulfonyl]ethane (16191-84-7)

Guidance literature:

With pyridine; thionyl chloride; In toluene; for 3h; Heating;

DOI:10.1021/jm060414o

Reference yield:

2-[(4-Chlorophenyl)thio]ethanol (13457-98-2) → 2-chloro-1-[(4-chlorophenyl)sulfonyl]ethane (16191-84-7)

Guidance literature:

With hydrogenchloride; sodium hypochlorite;

upstream raw materials:

2-[(4-Chlorophenyl)thio]ethanol

ethene

4-chlorobenzenesulfonyl chloride

2-chloroethyl 4-chlorophenyl sulfide

Downstream raw materials:

C₁₀H₁₁ClO₄S₂

N-<2-(4-Chlor-phenylsulfonyl)-aethyl>-tert-butylamin

p-chlorophenyl vinyl sulfone

3-(4-chlorphenylsulfonyl)propionitril

Refernces

• 1、 Padmavathi, Venkatapuram,Venkatesh, Bhumireddy Chinnachennaiahgari,Premakumari, Chokkappagari,Padmaja, Adivireddy. "Synthesis of a new class of arylsulfonylethylsulfonylmethyloxazolines and thiazolines". . p. 646 - 651. Retrieved 2012/09/07.
• 2、 Abdel-Wahab, Aboel-Magd A.,El-Khawaga, Ahmed M.,El-Zohry, Maher F.,Khalaf, Ali A.. "MODERN FRIEDEL-CRAFTS CHEMISTRY. XI. CYCLIZATION OF ARYL HALOALKYL SULFONES, ARYLSULFONYLACYL CHLORIDES AND THEIR CORRESPONDING SULFIDES". . p. 31 - 44. Retrieved 2007/10/02.