4,4'-(butane-2,3-diyl)bis(chlorobenzene)

Base Information

• Chemical Name: 4,4'-(butane-2,3-diyl)bis(chlorobenzene)
• CAS No.: 606126-63-0
• Molecular Formula: C₁₆H₁₆Cl₂
• Molecular Weight: 279.209
• Mol file: 606126-63-0.mol

Synonyms:4,4'-(butane-2,3-diyl)bis(chlorobenzene)

Chemical Property of 4,4'-(butane-2,3-diyl)bis(chlorobenzene)

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4,4'-(butane-2,3-diyl)bis(chlorobenzene)

There total 7 articles about 4,4'-(butane-2,3-diyl)bis(chlorobenzene) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

C17H12ClNO4 → 4,4'-(butane-2,3-diyl)bis(chlorobenzene) (606126-63-0)

Guidance literature:

With C₅₅H₄₆N₄O₄W; N-ethyl-N,N-diisopropylamine; In acetonitrile; at 20 ℃; for 3h; Irradiation;

DOI:10.1039/d0sc01340d

Reference yield: 82.0%

1-Chloro-4-iodobenzene (637-87-6) + ethene (74-85-1) → 4,4'-(butane-2,3-diyl)bis(chlorobenzene) (606126-63-0)

Guidance literature:

With nickel(II) iodide; N,N,N,N,-tetramethylethylenediamine; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 100 ℃; for 24h; under 12929 Torr; Schlenk technique; Sealed tube; Irradiation;

DOI:10.1016/j.chempr.2018.10.006

Reference yield: 81.0%

bromochlorobenzene (106-39-8) + ethene (74-85-1) → 4,4'-(butane-2,3-diyl)bis(chlorobenzene) (606126-63-0)

Guidance literature:

With nickel(II) iodide; N,N,N,N,-tetramethylethylenediamine; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; N-ethyl-N,N-diisopropylamine; In dimethyl sulfoxide; at 100 ℃; for 24h; under 12929 Torr; Schlenk technique; Sealed tube; Irradiation;

DOI:10.1016/j.chempr.2018.10.006

upstream raw materials:

methylmagnesium chloride

(4-chlorophenyl)dichloromethane

1-(1-bromoethyl)-4-chlorobenzene

bromochlorobenzene

Refernces

• 1、 Sun, Han-Li,Wang, Jun-Jie,Yang, Fan,Ye, Wei-Ting,Zhu, Rong. "Dual Cobalt and Photoredox Catalysis Enabled Intermolecular Oxidative Hydrofunctionalization". . p. 4983 - 4989. Retrieved 2020/05/27.
• 2、 Li, Jiesheng,Luo, Yixin,Cheo, Han Wen,Lan, Yu,Wu, Jie. "Photoredox-Catalysis-Modulated, Nickel-Catalyzed Divergent Difunctionalization of Ethylene". supporting information. p. 192 - 203. Retrieved 2019/01/21.