1-Bromo-2-(bromomethyl)naphthalene

Base Information

• Chemical Name: 1-Bromo-2-(bromomethyl)naphthalene
• CAS No.: 37763-43-2
• Molecular Formula: C11H8Br2
• Molecular Weight: 299.993
• Hs Code.: 2942000090
• European Community (EC) Number: 640-269-7
• NSC Number: 97068
• UNII: U4ZZQ55KVB
• DSSTox Substance ID: DTXSID50191210
• Nikkaji Number: J42.422F
• Wikidata: Q83063722
• Mol file: 37763-43-2.mol

Synonyms:1-bromo-2-(bromomethyl)naphthalene;37763-43-2;1-Bromo-2-bromomethylnaphthalene;NAPHTHALENE, 1-BROMO-2-BROMOMETHYL-;Naphthalene, 1-bromo-2-(bromomethyl)-;NSC 97068;U4ZZQ55KVB;BRN 1943405;C11H8Br2;NSC-97068;3-05-00-01633 (Beilstein Handbook Reference);NSC97068;UNII-U4ZZQ55KVB;NCIOpen2_006237;WLN: L66J BE C1E;1-Bromo-2-bromethylnaphthalene;SCHEMBL4698955;C11-H8-Br2;DTXSID50191210;2-(Bromomethyl)-1-bromonaphthalene;1-bromo-2-(bromomethyl)-naphthalene;1-Bromonaphthalen-2-ylmethyl bromide;MFCD00046369;STL268080;AKOS005203374;PS-9959;AC-27922;BP-12596;LS-94440;B1607;FT-0639404;EN300-307732;A823858;1-Bromo-2-(bromomethyl)naphthalene, >=96.0% (GC)

Chemical Property of 1-Bromo-2-(bromomethyl)naphthalene

Chemical Property:

• Vapor Pressure: 3.82E-05mmHg at 25°C
• Melting Point: 108oC
• Boiling Point: 363.2°C at 760 mmHg
• Flash Point: 202.5°C
• PSA: 0.00000
• Density: 1.772g/cm³
• LogP: 4.49720
• XLogP3: 4.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 1
• Exact Mass: 299.89723
• Heavy Atom Count: 13
• Complexity: 170

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Bromo-2-(bromomethyl)naphthalene ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38-41
• Safety Statements: 26-36/37/39-39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C2C(=C1)C=CC(=C2Br)CBr

Technology Process of 1-Bromo-2-(bromomethyl)naphthalene

There total 4 articles about 1-Bromo-2-(bromomethyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.5%

2-Methylnaphthalene (91-57-6,34468-07-0) → 1-bromo-2-(bromomethyl)naphthalene (37763-43-2) + 1-bromo-2-methylnaphtalene (2586-62-1) + 7-bromo-1-bromomethyl-naphthalene (189693-08-1) + 2-bromomethylnaphthyl bromide (939-26-4)

Guidance literature:

With bromine; lanthanum(III) acetate; In n-heptane; at 60 - 62 ℃; for 5.5h; Yields of byproduct given; illuminating with visible light;

DOI:10.1080/00397919708006823

Reference yield: 19.0%

2-Methylnaphthalene (91-57-6,34468-07-0) → 1-bromo-2-(bromomethyl)naphthalene (37763-43-2) + 1-bromo-2-methylnaphtalene (2586-62-1) + 2-bromomethylnaphthyl bromide (939-26-4)

Guidance literature:

With bromine; lanthanum(III) acetate; In tetrachloromethane; at 60 ℃; Irradiation;

Reference yield:

carbon disulfide (75-15-0,12122-00-8) + bromine (7726-95-6) + 2-Methylnaphthalene (91-57-6,34468-07-0) → 1-bromo-2-(bromomethyl)naphthalene (37763-43-2) + 1-bromo-2-methylnaphtalene (2586-62-1)

Guidance literature:

upstream raw materials:

2-Methylnaphthalene

carbon disulfide

bromine

Downstream raw materials:

1-bromo-2-naphthaldehyde

2-(1-bromonaphthalen-2-yl)acetonitrile

2-(1-bromonaphth-2-ylmethyl)-2-nitrocyclohexanone

2-[(1-bromonaphthalen-2-yl)methyl]-3-hydroxy-2-cyclohexen-1-one

Refernces

• 1、 Ouertani, Mohsen,Girard, Pierre,Kagan, Henry B.. "The easy preparation of many benzylic bromides using molecular bromine as a halogenating in the presence of catalytic amounts of lanthanum tri-acetate". . p. 327 - 328. Retrieved 2007/10/02.