[(1S)-1-carboxyethyl]azanium;chloride

Base Information

• Chemical Name: [(1S)-1-carboxyethyl]azanium;chloride
• CAS No.: 6003-05-0
• Molecular Formula: C₃H₇NO₂*ClH
• Molecular Weight: 125.555
• Hs Code.: 2922499990
• Mol file: 6003-05-0.mol

Synonyms:

Chemical Property of [(1S)-1-carboxyethyl]azanium;chloride

Chemical Property:

• Vapor Pressure: 2.17E-05mmHg at 25°C
• Refractive Index: 1.576
• Boiling Point: 212.9 °C at 760 mmHg
• Flash Point: 82.6 °C
• PSA: 63.32000
• Density: 1.546g/cm³
• LogP: 0.92050
• Storage Temp.: 2-8°C
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 1
• Exact Mass: 125.0243562
• Heavy Atom Count: 7
• Complexity: 61.8

Purity/Quality:

99%, ^*data from raw suppliers

L-Alanine hydrochloride solution 100?mM amino acid in 0.1 M HCl, analytical standard ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C(=O)O)[NH3+].[Cl-]
• Isomeric SMILES: C[C@@H](C(=O)O)[NH3+].[Cl-]

Technology Process of [(1S)-1-carboxyethyl]azanium;chloride

There total 16 articles about [(1S)-1-carboxyethyl]azanium;chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

L-alanin (56-41-7,25191-17-7,18875-37-1) → L-alanine hydrochloride (6003-05-0,16428-74-3,25616-13-1,26570-06-9)

Guidance literature:

With hydrogenchloride; In water; for 0.5h;

Reference yield: 99.0%

L-N-Boc-Ala (15761-38-3) → L-alanine hydrochloride (6003-05-0,16428-74-3,25616-13-1,26570-06-9)

Guidance literature:

With sulfuric acid; sodium chloride; In neat (no solvent); at 20 ℃; for 1h; Sealed tube;

DOI:10.1039/d1ob00728a

Reference yield: 95.0%

(αS,3R)-4,4-dimethyl-2-oxo-1-phenylpyrrolidin-3-yl α-phthalimidopropanoate (226387-97-9,496785-30-9) → L-alanine hydrochloride (6003-05-0,16428-74-3,25616-13-1,26570-06-9)

Guidance literature:

With hydrogenchloride; acetic acid; for 4h; Heating;

DOI:10.1016/S0957-4166(99)00018-X

upstream raw materials:

L-alanin

L-Alanine ethyl ester

L-N-Boc-Ala

N-benzyl-(S)-alanine

Downstream raw materials:

N-(trifluoroacetyl)-L-alanine

N-[(9H-fluoren-9-ylmethoxy)carbonyl]-L-alanine

isopropyl L-alanine

(S)-Alaninol

Refernces

• 1、 Ghazaryan,Giester,Fleck,Petrosyan. "L-Alanine halogenides with L-alanine L-alaninium dimeric cation". . p. 428 - 441. Retrieved 2018/05/03.
• 2、 Cho, Ji Young,Kang, Ji Young,Hong, Yong Ki,Baek, Hyo Hyun,Shin, Hyoun Woong,Kim, Myoung Sug. "Isolation and structural determination of the antifouling diketopiperazines from marine-derived Streptomyces praecox 291-11". experimental part. p. 1116 - 1121. Retrieved 2012/10/07.