2,3-Dihydro-1H-cyclopenta[b]quinoline

Base Information

• Chemical Name: 2,3-Dihydro-1H-cyclopenta[b]quinoline
• CAS No.: 5661-06-3
• Molecular Formula: C12H11N
• Molecular Weight: 169.226
• Hs Code.: 2933990090
• Mol file: 5661-06-3.mol

Synonyms:

Chemical Property of 2,3-Dihydro-1H-cyclopenta[b]quinoline

Chemical Property:

• Vapor Pressure: 0.000825mmHg at 25°C
• Boiling Point: 315.1°C at 760 mmHg
• Flash Point: 136.9°C
• PSA: 12.89000
• Density: 1.16g/cm³
• LogP: 2.72350
• Storage Temp.: 2-8°C

Purity/Quality:

98%,99%, ^*data from raw suppliers

2,3-Dihydro-1H-cyclopenta[b]quinoline 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3-Dihydro-1H-cyclopenta[b]quinoline

There total 36 articles about 2,3-Dihydro-1H-cyclopenta[b]quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

(E)-2-(2-aminobenzylidene)cyclopentanone → 2,3-dihydro-1H-cyclopenta[b]quinoline (5661-06-3)

Guidance literature:

In tetrahydrofuran; for 12h; Irradiation;

DOI:10.1039/c7ob00558j

Reference yield: 91.0%

Cyclopentanol (96-41-3) + 2-Nitrobenzyl alcohol (612-25-9) → 2,3-dihydro-1H-cyclopenta[b]quinoline (5661-06-3)

Guidance literature:

With C₂₂H₂₄ClIrN₃O⁽¹⁺⁾*Cl^(1-); potassium hydroxide; In water; at 120 ℃; for 24h; Green chemistry;

DOI:10.1016/j.jcat.2019.03.028

Reference yield: 86.0%

cyclopentanone (120-92-3) + ortho-bromobenzaldehyde (6630-33-7) → 2,3-dihydro-1H-cyclopenta[b]quinoline (5661-06-3)

Guidance literature:

With D-glucose; copper(II) sulfate; L-proline; potassium hydroxide; In ethanol; water; at 90 ℃; for 7h;

DOI:10.1039/c4ra14138e

upstream raw materials:

8-chloro-2,3-dihydro-1H-cyclopenta[1,2-b]quinoline

o-aminobenzaldehyde

cyclopentanone

quinazoline

Downstream raw materials:

(E)-3-benzylidene-2,3-dihydro-1H-cyclopenta[b]quinoline

1,2-dihydro-cyclopenta[b]quinolin-3-one-(2,4-dinitro-phenylhydrazone)

1,2-dihydro-cyclopenta[b]quinolin-3-one-phenylhydrazone

C₂₁H₁₈N₂O₅

Refernces

• 1、 -. "Pincerlike manganese complex and preparation method thereof, related ligand and preparation method thereof, catalyst composition and application". Paragraph 0144; 0146; 0147-0151. . Retrieved 2021/07/31.
• 2、 -. "A cobalt-catalyzed method for synthesizing quinoline and quinazoline compounds". Paragraph 0011; 0049. . Retrieved 2022/01/10.