3,5-Diphenyl-4-nitroisoxazoline

Base Information

• Chemical Name: 3,5-Diphenyl-4-nitroisoxazoline
• CAS No.: 62260-73-5
• Molecular Formula: C₁₅H₁₂N₂O₃
• Molecular Weight: 268.272
• Mol file: 62260-73-5.mol

Synonyms:3,5-Diphenyl-4-nitroisoxazoline

Chemical Property of 3,5-Diphenyl-4-nitroisoxazoline

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,5-Diphenyl-4-nitroisoxazoline

There total 5 articles about 3,5-Diphenyl-4-nitroisoxazoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 52.0%

benzonitrile oxide (873-67-6) + nitrostyrene (5153-67-3) → trans-3,4-diphenyl-5-nitro-Δ2-isoxazoline (50899-23-5,115335-20-1) + trans-3,5-diphenyl-4-nitro-Δ2-isoxazoline (50899-24-6,62260-73-5,96751-51-8)

Guidance literature:

In diethyl ether; for 24h; Ambient temperature;

Reference yield:

2-nitro-1-phenylethan-1-one oxime (21205-24-3) + benzaldehyde (100-52-7) → trans-3,5-diphenyl-4-nitro-Δ2-isoxazoline (50899-24-6,62260-73-5,96751-51-8)

Guidance literature:

With 3-azapentane-1,5-diamine; In methanol; at 18 - 25 ℃;

Reference yield:

benzonitrile oxide (873-67-6) + nitrostyrene (5153-67-3) → 3,5-Diphenyl-4-nitroisoxazoline (62260-73-5)

Guidance literature:

With diethyl ether;

upstream raw materials:

benzonitrile oxide

nitrostyrene

2-nitro-1-phenylethan-1-one oxime

benzaldehyde

Downstream raw materials:

2-(m-tolyl)-4-phenyl-5-benzoyl-1,2,3-triazole

2-(p-tolyl)-4-phenyl-5-benzoyl-1,2,3-triazole

(2,5-diphenyl-2H-1,2,3-triazol-4-yl)(phenyl)methanone

3-(3-phenyl-5-phenylisoxazol-4-yl)propionitrile

Refernces

• 1、 Baranski, Andrzej. "SYNTHESIS AND PROPERTIES OF AZOLS AND THEIR DERIVATIVES. PART V. REGIOCHEMISTRY IN CYCLOADDITION REACTIONS OF BENZONITRILE N-OXIDE WITH β-SUBSTITUTED NITROETHYLENES". . p. 257 - 266. Retrieved 2007/10/02.