Decaserpil

Base Information

• Chemical Name: Decaserpil
• CAS No.: 865-04-3
• Molecular Formula: C33H40 N2 O9
• Molecular Weight: 608.689
• European Community (EC) Number: 212-733-5
• NSC Number: 169423
• DSSTox Substance ID: DTXSID80862446
• Wikipedia: Methoserpidine
• NCI Thesaurus Code: C175134
• Mol file: 865-04-3.mol

Synonyms:Methoserpidine;Decaserpil;Canescine 10-methoxyderivative;10-Methoxy-11-desmethoxyreserpine;865-04-3;Decaserpin;Decaserpine;Decoserpyl;Deaserpyl;Decaserpyl plus;(-)-10-Methoxydeserpidine;methyl 7,18-dimethoxy-17-(3,4,5-trimethoxybenzoyl)oxy-1,3,11,12,14,15,16,17,18,19,20,21-dodecahydroyohimban-19-carboxylate;Yohimban-16-carboxylic acid, 10,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]-, methyl ester, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)-;NSC 169423;Methyl 10,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate;Methoserpedine;3.beta.,20.alpha.-Yohimban-16.beta.-carboxylic acid, 18.beta.-hydroxy-10,17.alpha.-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester);DTXSID80862446;ULBNWNUHGJLQHO-UHFFFAOYSA-N;NSC169423;Cyclobutanecarboxylicacid,1-amino-,methylester,hydrochloride(9CI);WLN: T F6 D5 C666 EM ON&&TTTJ JO1 SOVR CO1 DO1 EO1& TO1 UVO1;3-.beta.,20-.alpha.-Yohimban-16-.beta.-carboxylic acid, 18-.beta.-hydroxy-10,17-.alpha.-dimethoxy-,methyl ester, 3,4,5-trimethoxybenzoate;3.beta., 18.beta.-hydroxy-10,17.alpha.-dimethoxy-, methyl ester, 3,4,5-trimethoxybenzoate (ester);3.beta., 18.beta.-hydroxy-10,17.alpha.-dimethoxy-,methyl ester, 3,4,5-trimethoxybenzoate (ester);Methyl 10,17-dimethoxy-18-[(3,4,5-trimethoxybenzoyl)oxy]yohimban-16-carboxylate, (3.beta.,16.beta.,17.alpha.,18.beta.,20.alpha.)- #

Chemical Property of Decaserpil

Chemical Property:

• Vapor Pressure: 1.91E-19mmHg at 25°C
• Melting Point: 171°C
• Refractive Index: 1.6260 (estimate)
• Boiling Point: 700.1°C at 760 mmHg
• Flash Point: 377.2°C
• PSA: 117.78000
• Density: 1.32g/cm³
• LogP: 4.10900
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 10
• Rotatable Bond Count: 10
• Exact Mass: 608.27338086
• Heavy Atom Count: 44
• Complexity: 1000

Purity/Quality:

99% ^*data from raw suppliers

METHOSERPIDINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1C(CC2CN3CCC4=C(C3CC2C1C(=O)OC)NC5=C4C=C(C=C5)OC)OC(=O)C6=CC(=C(C(=C6)OC)OC)OC

Technology Process of Decaserpil

There total 4 articles about Decaserpil which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-(5-methoxyindol-3-yl)ethylamine (608-07-1) → Deaserpyl (865-04-3)

Guidance literature:

ueber mehrere Zwischenstufen;

Reference yield:

→ Deaserpyl (865-04-3)

Guidance literature:

Reference yield:

→ 10,17-dimethoxy-18-(3,4,5-trimethoxy-benzoyloxy)-yohimbane-16-carboxylic acid methyl ester (865-04-3,42881-95-8)

Guidance literature:

Yohimben(VI) m. HClO4/FeCl3/Zn;

upstream raw materials:

2-(5-methoxyindol-3-yl)ethylamine

Refernces