Technology Process of 3,4-Dimethoxy-5-benzyloxyphenylaceticacid
There total 11 articles about 3,4-Dimethoxy-5-benzyloxyphenylaceticacid which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide;
In
ethanol;
for 20h;
Heating;
DOI:10.1021/ol0261635
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: SOCl2 / benzene / 12 h / 20 °C
1.2: dimethylsulfoxide; benzene / 20 °C
2.1: 98 percent / sodium hydroxide / ethanol / 20 h / Heating
With
sodium hydroxide; thionyl chloride;
In
ethanol; benzene;
DOI:10.1021/ol0261635
- Guidance literature:
-
Multi-step reaction with 8 steps
1.1: 89 percent / sodium hydroxide; Adogen 464(R) / CH2Cl2 / 15 h / 20 °C
2.1: sodium borohydride / tetrahydrofuran; methanol / 2 h
3.1: imidazole / dimethylformamide / 12 h / 20 °C
4.1: n-butyllithium / 1 h / -78 °C
4.2: trimethyl borate / 12 h / -78 - 20 °C
4.3: 78 percent / hydrogen peroxide / 12 h / 20 °C
5.1: 75 percent / potassium carbonate / acetone / 12 h / Heating
6.1: 100 percent / tetra-n-butylammonium fluoride / tetrahydrofuran / 2 h / 0 °C
7.1: SOCl2 / benzene / 12 h / 20 °C
7.2: dimethylsulfoxide; benzene / 20 °C
8.1: 98 percent / sodium hydroxide / ethanol / 20 h / Heating
With
1H-imidazole; sodium hydroxide; sodium tetrahydroborate; n-butyllithium; thionyl chloride; Adogen 464(R); tetrabutyl ammonium fluoride; potassium carbonate;
In
tetrahydrofuran; methanol; ethanol; dichloromethane; N,N-dimethyl-formamide; acetone; benzene;
DOI:10.1021/ol0261635