Isopropyl glycidyl ether

Base Information

• Chemical Name: Isopropyl glycidyl ether
• CAS No.: 4016-14-2
• Deprecated CAS: 126753-03-5
• Molecular Formula: C6H12 O2
• Molecular Weight: 116.16
• Hs Code.: 2910900090
• European Community (EC) Number: 223-672-9
• ICSC Number: 0171
• NSC Number: 46562,4127
• UN Number: 3271,1993
• UNII: 1V3116630G
• DSSTox Substance ID: DTXSID6025480
• Nikkaji Number: J35.468F
• Wikidata: Q2803610
• ChEMBL ID: CHEMBL1487011
• Mol file: 4016-14-2.mol

Synonyms:((1-methylethoxy)methyl)oxirane;(isopropoxymethyl)oxirane;isopropyl glycidyl ether

Chemical Property of Isopropyl glycidyl ether

Chemical Property:

• Appearance/Colour: colourless liquid
• Vapor Pressure: 11.6mmHg at 25°C
• Refractive Index: n20/D 1.410(lit.)
• Boiling Point: 131ºC at 760 mmHg
• Flash Point: 33.3 ºC
• PSA: 21.76000
• Density: 0.955 g/cm³
• LogP: 0.81020
• Storage Temp.: -20°C
• Solubility.: 188g/l
• Water Solubility.: 19g/L at 25℃
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 116.083729621
• Heavy Atom Count: 8
• Complexity: 70.9
• Transport DOT Label: Flammable Liquid

Purity/Quality:

98% ^*data from raw suppliers

Glycidyl Isopropyl Ether ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Flammable liquid with flash p 92F (33.33C). TLV: TWA 50 ppm; STEL 75 ppm. Skin, eye, and respiratory irritant.
• Hazard Codes: Xi
• Statements: 10-19-36/37/38-43
• Safety Statements: 16-26-36/37

MSDS Files:

Useful:

• Chemical Classes: Plastics & Rubber -> Glycidyl Ethers
• Canonical SMILES: CC(C)OCC1CO1
• Inhalation Risk: A harmful contamination of the air can be reached rather quickly on evaporation of this substance at 20 °C.
• Effects of Short Term Exposure: The substance is irritating to the eyes, skin and respiratory tract. Inhalation of the vapour may cause lung oedema. The substance may cause effects on the central nervous system. Exposure above the OEL could cause lowering of consciousness.
• Uses: Glycidyl isopropyl ether is a stabilizer of chlorinated solvents, and viscosity reducer of epoxy resins. Isopropyl glycidyl ether (IGE) is used to sta-bilize chlorinated solvents and as a viscosityreducer of epoxy resins. Reactive diluent for epoxy resins; stabilizer for organic compounds; chemical intermediate for synthesis of ethers and esters

Technology Process of Isopropyl glycidyl ether

There total 6 articles about Isopropyl glycidyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C13H20O5S → glycidyl isopropyl ether (4016-14-2)

Guidance literature:

With n-butyllithium; In diethyl ether;

Reference yield:

3-isopropoxyprop-1-ene (6140-80-3) → glycidyl isopropyl ether (4016-14-2)

Guidance literature:

With 3-chloro-benzenecarboperoxoic acid; In dichloromethane; at 45 ℃; for 48h;

Reference yield:

→ glycidyl isopropyl ether (4016-14-2)

Guidance literature:

With sodium hydroxide; diethyl ether;

DOI:10.1021/jo01170a015

upstream raw materials:

sodium isopropylate

epichlorohydrin

3-isopropoxyprop-1-ene

isopropyl alcohol

Downstream raw materials:

2-Isopropoxymethyl-6-nitro-2,3-dihydro-imidazo[2,1-b]oxazole

1-isopropoxy-3-p-tolylamino-propan-2-ol

2,4-bis{[4-(3-(2-propyloxy)-2-hydroxypropyloxy)-2-hydroxyphenyl]}-6-(4-methoxyphenyl)-1,3,5-triazine

3-isopropoxy-1-pentachlorophenylthio-2-propanol

Refernces

• 1、 Zaitsev, L. M.,Korotkii, Yu. V.,Krasavtsev, I. I.,Lozinskii, M. O.. "SYNTHESIS AND UTEROSTIMULATING ACTIVITY OF DERIVATIVES OF 1-DIALKYLAMINO-3-ALKOXY-2-PROPANOL". . p. 492 - 495. Retrieved 2007/10/02.
• 2、 Leclerc, Gerard,Bieth, Nicole,Schwartz, Jean. "Synthesis and β-Adrenergic Blocking Activity of New Aliphatic Oxime Ethers". . p. 620 - 624. Retrieved 2007/10/02.