1-Acetoxy-4-acetoxyimino-1,4-dihydroquinoline

Base Information

• Chemical Name: 1-Acetoxy-4-acetoxyimino-1,4-dihydroquinoline
• CAS No.: 18061-48-8
• Molecular Formula: C13H12 N2 O4
• Molecular Weight: 260.249
• Hs Code.: 2933499090
• Mol file: 18061-48-8.mol

Synonyms:1-AAIDQ;1-acetoxy-4-acetoxyimino-1,4-dihydroquinoline

Chemical Property of 1-Acetoxy-4-acetoxyimino-1,4-dihydroquinoline

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 353.9°Cat760mmHg
• Flash Point: 167.8°C
• PSA: 69.89000
• Density: 1.26g/cm³
• LogP: 0.99520
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 6
• Rotatable Bond Count: 4
• Exact Mass: 260.07970687
• Heavy Atom Count: 19
• Complexity: 430

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=O)ON=C1C=CN(C2=CC=CC=C12)OC(=O)C
• Isomeric SMILES: CC(=O)O/N=C/1\C=CN(C2=CC=CC=C12)OC(=O)C

Technology Process of 1-Acetoxy-4-acetoxyimino-1,4-dihydroquinoline

There total 2 articles about 1-Acetoxy-4-acetoxyimino-1,4-dihydroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-nitroquinoline-N-oxide (56-57-5) + acetic anhydride (108-24-7) → 1-acetoxy-4-(acetoxyimino)-1,4-dihidroquinoline (18061-48-8)

Guidance literature:

With ascorbic acid; Multistep reaction; 2.) acetic acid;

DOI:10.1021/ja00272a077

Reference yield:

acetic anhydride (108-24-7) + 1-acetoxy-4-(hydroxyimino)-1,4-dihydroquinoline hydrochloride (80255-01-2) → 1-acetoxy-4-(acetoxyimino)-1,4-dihydroquinoline (18061-48-8)

Guidance literature:

Product distribution;

DOI:10.1016/S0040-4039(01)81860-8

Reference yield: 30.0%

1-acetoxy-4-(acetoxyimino)-1,4-dihydroquinoline (18061-48-8) → 4-(acetylamino)-3-hydroxyquinoline (117942-19-5) + 4-nitrosoquinoline (80255-02-3) + [4,4']azoxyquinoline-1,1'-dioxide (1168-15-6)

Guidance literature:

With 2,2,2-trifluoroethanol; for 24h; Ambient temperature;

DOI:10.1021/jo00263a027

upstream raw materials:

acetic anhydride

1-acetoxy-4-(hydroxyimino)-1,4-dihydroquinoline hydrochloride

4-nitroquinoline-N-oxide

Downstream raw materials:

1-hydroxy-4-(acetoxyimino)-1,4-dihydroquinoline

1-acetoxy-4-(hydroxyimino)-1,4-dihydroquinoline hydrochloride

4-(acetylamino)-3-hydroxyquinoline

4-nitrosoquinoline

Refernces