(E)-1-(4-methylphenyl)propanone O-benzyl oxime

Base Information

• Chemical Name: (E)-1-(4-methylphenyl)propanone O-benzyl oxime
• CAS No.: 937371-82-9
• Molecular Formula: C₁₇H₁₉NO
• Molecular Weight: 253.344
• Mol file: 937371-82-9.mol

Synonyms:(E)-1-(4-methylphenyl)propanone O-benzyl oxime

Chemical Property of (E)-1-(4-methylphenyl)propanone O-benzyl oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (E)-1-(4-methylphenyl)propanone O-benzyl oxime

There total 2 articles about (E)-1-(4-methylphenyl)propanone O-benzyl oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1-p-tolylpropan-1-one oxime (54582-25-1) → (E)-1-(4-methylphenyl)propanone O-benzyl oxime (937371-82-9)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃;

DOI:10.1021/ol0704791

Reference yield:

N-benzyloxyamine (622-33-3) + 4'-methylpropiophenone (5337-93-9) → (E)-1-(4-methylphenyl)propanone O-benzyl oxime (937371-82-9)

Guidance literature:

With benzene;

Reference yield:

(E)-1-(4-methylphenyl)propanone O-benzyl oxime (937371-82-9) + acetic anhydride (108-24-7) → (S)-N-[1-(4-methylphenyl)propyl]acetamide + (R)-N-[1-(4-methylphenyl)propyl]acetamide

Guidance literature:

(E)-1-(4-methylphenyl)propanone O-benzyl oxime; With sodium tetrahydroborate; borane; enantiopure spiroborate ester; In 1,4-dioxane; for 36h;

acetic anhydride; With dmap; triethylamine; In dichloromethane; at 0 ℃; for 3h; Further stages. Title compound not separated from byproducts.;

DOI:10.1021/ol0704791

upstream raw materials:

N-benzyloxyamine

4'-methylpropiophenone

1-p-tolylpropan-1-one oxime

Refernces