Methacrylamide

Base Information

• Chemical Name: Methacrylamide
• CAS No.: 79-39-0
• Molecular Formula: C4H7NO
• Molecular Weight: 85.1057
• Hs Code.: 2924199090
• European Community (EC) Number: 201-202-3
• NSC Number: 24147,23772
• UNII: K67NG89J77
• DSSTox Substance ID: DTXSID8029600
• Nikkaji Number: J38.885H
• Wikipedia: Methacrylamide
• Wikidata: Q1549805
• Metabolomics Workbench ID: 57856
• ChEMBL ID: CHEMBL158237
• Mol file: 79-39-0.mol

Synonyms:methacrylamide

Chemical Property of Methacrylamide

Chemical Property:

• Appearance/Colour: white to very slightly yellow crystals
• Melting Point: 108 °C
• Boiling Point: 211.5 °C at 760 mmHg
• Flash Point: 81.7 °C
• PSA: 43.09000
• Density: 0.942 g/cm³
• LogP: 0.74810
• Water Solubility.: 202 g/L (20℃)
• XLogP3: 0.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 85.052763847
• Heavy Atom Count: 6
• Complexity: 85.5

Purity/Quality:

99.8 % ^*data from raw suppliers

Safty Information:

• Pictogram(s): Xn
• Hazard Codes: Xn:Harmful
• Statements: R22:; R36/37/38:
• Safety Statements: S26:; S36/37:

MSDS Files:

SDS file from LookChem

Useful:

• Chemical Classes: Plastics & Rubber -> Other Monomers
• Canonical SMILES: CC(=C)C(=O)N

Technology Process of Methacrylamide

There total 20 articles about Methacrylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methacrylonitrile (126-98-7,25067-61-2) → Methacrylamide (79-39-0)

Guidance literature:

With C₂₉H₄₆NiOP₂; water; In isopropyl alcohol; at 80 ℃; for 6h; Reagent/catalyst; Sealed tube;

DOI:10.1039/c4dt03902e

Reference yield: 85.0%

methacryloyl anhydride (760-93-0) → Methacrylamide (79-39-0)

Guidance literature:

With ammonia; at 0 - 5 ℃; for 1h; Green chemistry;

DOI:10.1016/j.jorganchem.2019.04.024

Reference yield: 82.0%

→ Methacrylamide (79-39-0)

Guidance literature:

upstream raw materials:

β-methoxy-isobutyric acid amide

2-hydroxy-2-methylpropanenitrile

methacrylic acid methyl ester

α-sulfooxy-isobutyric acid amid; ammonium salt

Downstream raw materials:

5-exo-Carbamoyl-5-endo-methyl-norbornen-(2)

3-(diphenylphosphoryl)-2-methylpropanenitrile

2,3-epoxy-2-methylpropanamide

3,4-dihydro-5-(4-methoxyphenyl)-3,6-dimethyl-2(1H)-pyridinone

Refernces

• 1、 Sayed, Wafaa M.,Abed, Yahia M.,Gad, El-Shafie A.M.,Salem, Tousson A.. "Comparison between the electric conductivity of polyhydroxamic acids of different origin". . p. 245 - 252. Retrieved 1998.
• 2、 Borau-Garcia,Gutsulyak,Burford,Piers. "Selective hydration of nitriles to amides catalysed by PCP pincer supported nickel(ii) complexes". . p. 12082 - 12085. Retrieved 2016/01/15.