Isonicotinic acid, (1-(4-pyridyl)ethylidene)hydrazide

Base Information

• Chemical Name: Isonicotinic acid, (1-(4-pyridyl)ethylidene)hydrazide
• CAS No.: 91803-29-1
• Molecular Formula: C₁₃H₁₂N₄O
• Molecular Weight: 240.264
• Mol file: 91803-29-1.mol

Synonyms:BRN 0209030;Isonicotinylhydrazone de la 4-acetylpyridine [French];4-Pyridinecarboxylic acid, (1-(4-pyridinyl)ethylidene)hydrazide;ISONICOTINIC ACID, (1-(4-PYRIDYL)ETHYLIDENE)HYDRAZIDE;Isonicotinylhydrazone de la 4-acetylpyridine;4-22-00-00660 (Beilstein Handbook Reference);91803-29-1;LS-85017

Chemical Property of Isonicotinic acid, (1-(4-pyridyl)ethylidene)hydrazide

Chemical Property:

• Boiling Point: 411.285oC at 760 mmHg
• Flash Point: 202.538oC
• PSA: 58.45000
• Density: 1.165g/cm3
• LogP: 2.12910
• XLogP3: 0.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 3
• Exact Mass: 240.10111102
• Heavy Atom Count: 18
• Complexity: 293

Purity/Quality:

ISONICOTINIC ACID (1-(4-PYRIDYL)ETHYLIDENE)HYDRAZIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC=NN(C1=CC=NC=C1)C(=O)C2=CC=NC=C2
• Isomeric SMILES: C/C=N/N(C1=CC=NC=C1)C(=O)C2=CC=NC=C2

Technology Process of Isonicotinic acid, (1-(4-pyridyl)ethylidene)hydrazide

There total 2 articles about Isonicotinic acid, (1-(4-pyridyl)ethylidene)hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methyl (4-pyridyl) ketone (1122-54-9) + isoniazid (54-85-3,7640-37-1) → isonicotinic acid-(1-[4]pyridyl-ethylidenehydrazide) (91803-29-1)

Guidance literature:

With isopropyl alcohol;

DOI:10.1021/jo01109a024

Reference yield:

→ isonicotinic acid-(1-[4]pyridyl-ethylidenehydrazide) (91803-29-1)

Guidance literature:

Isonicotinsaeurehydrazid, 4-Acetyl-pyridin, etwas Eg., A., (sieden);

upstream raw materials:

methyl (4-pyridyl) ketone

isoniazid