4-(Diethylamino)-2-methoxybenzaldehyde

Base Information

• Chemical Name: 4-(Diethylamino)-2-methoxybenzaldehyde
• CAS No.: 55586-68-0
• Molecular Formula: C12H17 N O2
• Molecular Weight: 207.272
• Hs Code.: 2922390090
• European Community (EC) Number: 850-122-0
• DSSTox Substance ID: DTXSID50354742
• Nikkaji Number: J503.131A
• Wikidata: Q82133119
• ChEMBL ID: CHEMBL1538172
• Mol file: 55586-68-0.mol

Synonyms:55586-68-0;4-(diethylamino)-2-methoxybenzaldehyde;4-Diethylamino-2-methoxy-benzaldehyde;4-DIETHYLAMINO-2-METHOXYBENZALDEHYDE;Benzaldehyde, 4-(diethylamino)-2-methoxy-;MFCD02277405;4-diethylamino-o-anisaldehyde;Cambridge id 6442543;Oprea1_486341;Oprea1_664630;MLS000711797;SCHEMBL2950989;CHEMBL1538172;DTXSID50354742;HMS2649B03;STK201266;AKOS000113614;AC-4481;CS-W022013;DS-1763;SMR000281564;2-methoxy-4-(N,N-diethylamino)benzaldehyde;FT-0600829;AB00107910-01;A830713;4-(Diethylamino)-2-methoxybenzaldehyde, AldrichCPR;J-513712;4-(diethylamino)-2-methoxy-benzaldehyde;4-Diethylamino-2-methoxybenzaldehyde

Chemical Property of 4-(Diethylamino)-2-methoxybenzaldehyde

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 334.8°Cat760mmHg
• Flash Point: 156.3°C
• PSA: 29.54000
• Density: 1.056g/cm³
• LogP: 2.35390
• Storage Temp.: under inert gas (nitrogen or Argon) at 2-8°C
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 207.125928785
• Heavy Atom Count: 15
• Complexity: 192

Purity/Quality:

99.5% ^*data from raw suppliers

4-Diethylamino-2-methoxy-benzaldehyde ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,T
• Statements: 25
• Safety Statements: 45

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)C1=CC(=C(C=C1)C=O)OC

Technology Process of 4-(Diethylamino)-2-methoxybenzaldehyde

There total 5 articles about 4-(Diethylamino)-2-methoxybenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

4-(Diethylamino)salicylaldehyde (17754-90-4) + methyl iodide (74-88-4) → 2-Methoxy-4-diethylaminobenzaldehyde (55586-68-0)

Guidance literature:

4-(Diethylamino)salicylaldehyde; With potassium hydroxide; potassium carbonate; In acetonitrile; at 80 ℃; for 0.166667h;

methyl iodide; In acetonitrile; at 80 ℃; for 2h; Further stages.;

DOI:10.1021/jp0476390

Reference yield: 84.8%

methyl bromide (74-83-9) + 4-(Diethylamino)salicylaldehyde (17754-90-4) → 2-Methoxy-4-diethylaminobenzaldehyde (55586-68-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 50 ℃; for 8h;

DOI:10.1016/j.dyepig.2010.11.009

Reference yield: 60.0%

4-fluoro-2-methoxybenzaldehyde (450-83-9) + diethylamine (109-89-7) → 2-Methoxy-4-diethylaminobenzaldehyde (55586-68-0)

Guidance literature:

With potassium carbonate; In ethanol; for 4.5h; Reflux;

DOI:10.1039/d0tb00149j

upstream raw materials:

4-(Diethylamino)salicylaldehyde

methyl iodide

methyl bromide

4-fluoro-2-methoxybenzaldehyde

Downstream raw materials:

1-(4-diethylamino-2-methoxyphenyl)ethanol

C₂₈H₃₄N₆O₂

Refernces

• 1、 Adhikari, Susanta,Adhikary, Arghya,Das, Manas kumar,Ghosh, Avijit,Guria, Subhajit,Mishra, Tanushree. "X-ray structurally characterized quinoline based fluorescent probes for pH sensing: Application in intracellular pH imaging; DFT calculations and fluorescent labelling". . . Retrieved 2020/12/17.
• 2、 Jadhav, Manoj M.,Vaghasiya, Jayraj V.,Patil, Dinesh,Soni, Saurabh S.,Sekar, Nagaiyan. "Synthesis of novel colorants for DSSC to study effect of alkyl chain length alteration of auxiliary donor on light to current conversion efficiency". . p. 119 - 129. Retrieved 2019/04/05.