2,3,4,5-tetramethoxyphenylformate

Base Information

• Chemical Name: 2,3,4,5-tetramethoxyphenylformate
• CAS No.: 86475-21-0
• Molecular Formula: C₁₁H₁₄O₆
• Molecular Weight: 242.229
• Mol file: 86475-21-0.mol

Synonyms:2,3,4,5-tetramethoxyphenylformate

Chemical Property of 2,3,4,5-tetramethoxyphenylformate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4,5-tetramethoxyphenylformate

There total 7 articles about 2,3,4,5-tetramethoxyphenylformate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,3,4,5-tetramethoxybenzaldehyde (65884-12-0) → 2,3,4,5-tetramethoxyphenylformate (86475-21-0)

Guidance literature:

With peracetic acid; perchloric acid; acetic anhydride; In acetic acid;

Reference yield:

2,3,4-trimethoxybenzaldehyde (2103-57-3) → 2,3,4,5-tetramethoxyphenylformate (86475-21-0)

Guidance literature:

Multi-step reaction with 5 steps

1: AcOOH, HClO₄, Ac₂O

2: KOH / ethanol / Heating

3: K₂CO₃ / acetone; benzene

4: POCl₃

5: AcOOH, HClO₄, Ac₂O / acetic acid

With peracetic acid; potassium hydroxide; perchloric acid; acetic anhydride; potassium carbonate; trichlorophosphate; In ethanol; acetic acid; acetone; benzene;

Reference yield:

1,2,3,4-tetramethoxybenzene (21450-56-6) → 2,3,4,5-tetramethoxyphenylformate (86475-21-0)

Guidance literature:

Multi-step reaction with 2 steps

1: POCl₃

2: AcOOH, HClO₄, Ac₂O / acetic acid

With peracetic acid; perchloric acid; acetic anhydride; trichlorophosphate; In acetic acid;

upstream raw materials:

2,3,4,5-tetramethoxybenzaldehyde

1,2,3,4-tetramethoxybenzene

2',3',4'-trimethoxyacetophenone

2,3,4-trimethoxyphenol

Downstream raw materials:

2,3,4,5-Tetramethoxyphenol

1,2,3,4,5-pentamethoxybenzene

2,4-diamino-5-(2,3,4,5,6-pentamethoxybenzyl)pyrimidine

β-methoxy-α-(2,3,4,5,6-pentamethoxybenzylidene)propionitrile

Refernces

• 1、 Asakawa, Tomohiro,Hiza, Aiki,Nakayama, Miho,Inai, Makoto,Oyama, Dai,Koide, Hiroyuki,Shimizu, Kosuke,Wakimoto, Toshiyuki,Harada, Norihiro,Tsukada, Hideo,Oku, Naoto,Kan, Toshiyuki. "PET imaging of nobiletin based on a practical total synthesis". supporting information; experimental part. p. 2868 - 2870. Retrieved 2011/04/22.
• 2、 Brossi,Sharma,Takahashi,et al.. "Tetramethoprim and pentamethoprim: Synthesis, antibacterial properties and X-ray structures". . p. 795 - 800. Retrieved 2007/10/02.