ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate

Base Information

• Chemical Name: ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate
• CAS No.: 306774-18-5
• Molecular Formula: C₁₄H₁₅NS₂
• Molecular Weight: 261.412
• Mol file: 306774-18-5.mol

Synonyms:ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate

Chemical Property of ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate

There total 1 articles about ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

carbon disulfide (75-15-0,12122-00-8) + 2-methyl-5-phenyl-1H-pyrrole (3042-21-5) + ethyl iodide (75-03-6) → Diethyl disulfide (110-81-6) + ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate (306774-18-5)

Guidance literature:

carbon disulfide; 2-methyl-5-phenyl-1H-pyrrole; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 3h;

ethyl iodide; In dimethyl sulfoxide; at 20 ℃; for 2h;

DOI:10.1016/S0040-4020(00)00641-4

Reference yield: 38.0%

ethyl iodide (75-03-6) + ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate (306774-18-5) + cyanoacetic acid amide (107-91-5) → 2-methyl-5-phenyl-1H-pyrrole (3042-21-5) + 3-(2-carbamoyl-2-cyano-1-ethylthioethenyl)-2-methyl-5-phenylpyrrole

Guidance literature:

cyanoacetic acid amide; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate; In dimethyl sulfoxide; at 110 ℃; for 1.5h;

ethyl iodide; In dimethyl sulfoxide; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(03)00679-8

Reference yield: 30.0%

ethyl iodide (75-03-6) + ethyl 2-cyanoacetate (105-56-6) + ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate (306774-18-5) → 2-methyl-5-phenyl-1H-pyrrole (3042-21-5) + 3-(2-carbethoxy-2-cyano-1-ethylthioethenyl)-2-methyl-5-phenylpyrrole

Guidance literature:

ethyl 2-cyanoacetate; With potassium hydroxide; In dimethyl sulfoxide; at 20 ℃; for 0.5h;

ethyl 2-methyl-5-phenylpyrrole-3-carbodithioate; In dimethyl sulfoxide; at 110 ℃; for 1.5h;

ethyl iodide; In dimethyl sulfoxide; at 20 ℃; for 2h;

DOI:10.1016/S0040-4039(03)00679-8

upstream raw materials:

carbon disulfide

2-methyl-5-phenyl-1H-pyrrole

ethyl iodide

Downstream raw materials:

2-methyl-5-phenyl-1H-pyrrole

Refernces