4-Dimethylaminobibenzyl

Base Information

• Chemical Name: 4-Dimethylaminobibenzyl
• CAS No.: 14301-09-8
• Molecular Formula: C16H19 N
• Molecular Weight: 225.334
• Hs Code.: 2921430090
• DSSTox Substance ID: DTXSID50162288
• Nikkaji Number: J81.747C
• Wikidata: Q83030907
• Mol file: 14301-09-8.mol

Synonyms:4-dimethylaminobibenzyl

Chemical Property of 4-Dimethylaminobibenzyl

Chemical Property:

• Vapor Pressure: 0.00019mmHg at 25°C
• Boiling Point: 328.4°Cat760mmHg
• Flash Point: 133.7°C
• PSA: 3.24000
• Density: 1.019g/cm³
• LogP: 3.53780
• XLogP3: 4.3
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 225.151749610
• Heavy Atom Count: 17
• Complexity: 198

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC=C(C=C1)CCC2=CC=CC=C2

Technology Process of 4-Dimethylaminobibenzyl

There total 8 articles about 4-Dimethylaminobibenzyl which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,N-dimethyl-4-(phenylethynyl)aniline (14301-08-7) → 4-N,N-dimethylaminobibenzyl (14301-09-8)

Guidance literature:

With palladium on activated charcoal; aluminium; In water; at 60 ℃; for 3h; Sealed tube;

DOI:10.1016/j.tet.2016.09.021

Reference yield: 85.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 4-Iodo-N,N-dimethylaniline (698-70-4) → 4-N,N-dimethylaminobibenzyl (14301-09-8)

Guidance literature:

With (1,2-dimethoxyethane)dichloronickel(II); sodium t-butanolate; In benzene; at 25 ℃; for 14h; regioselective reaction;

DOI:10.1039/C8SC05445B

Reference yield: 78.0%

4-(1-(Benzotriazol-1-yl)-1-benzylmethyl)-N,N-dimethylaniline (134627-80-8) → 4-N,N-dimethylaminobibenzyl (14301-09-8)

Guidance literature:

With lithium aluminium tetrahydride; In benzene; for 4h; Heating;

DOI:10.1016/S0040-4020(01)87221-5

upstream raw materials:

4-[(N-benzyl-hydrazino)-methyl]-N,N-dimethyl-aniline

4-(1-(Benzotriazol-1-yl)-1-benzylmethyl)-N,N-dimethylaniline

(E)-N,N-dimethyl-4-styrylbenzenamine

4-Iodo-N,N-dimethylaniline

Refernces

• 1、 Rayhan, Ummey,Kowser, Zannatul,Redshaw, Carl,Yamato, Takehiko. "Reduction of diphenylacetylene using Al powder in the presence of noble metal catalysts in water". supporting information. p. 6943 - 6947. Retrieved 2016/10/14.
• 2、 Katritzky, Alan R.,Lang, Hengyuan,Lan, Xiangfu. "Novel routes to 4-substituted N,N-dialkylanilines, N-alkylanilines and anilines". . p. 7445 - 7454. Retrieved 2007/10/02.