Propionamide, 2-ethylthio-2-methyl-

Base Information

• Chemical Name: Propionamide, 2-ethylthio-2-methyl-
• CAS No.: 7505-95-5
• Molecular Formula: C₆H₁₃NOS
• Molecular Weight: 147.241
• NSC Number: 402038
• DSSTox Substance ID: DTXSID30226019
• Nikkaji Number: J51.056D
• Wikidata: Q83105263
• Mol file: 7505-95-5.mol

Synonyms:Propionamide, 2-ethylthio-2-methyl-;7505-95-5;Propanamide, 2-(ethylthio)-2-methyl-;2-Ethylthio-2-methylpropionamide;2-Ethylmercapto-2-methylpropionamide;NSC 402038;BRN 1752854;2,2-Dimethyl-3-thiapentanamide;NSC402038;DTXSID30226019;AKOS006337576;NSC-402038;LS-124225

Chemical Property of Propionamide, 2-ethylthio-2-methyl-

Chemical Property:

• Vapor Pressure: 0.0157mmHg at 25°C
• Boiling Point: 256.1°C at 760 mmHg
• Flash Point: 108.7°C
• PSA: 68.39000
• Density: 1.034g/cm³
• LogP: 1.70370
• XLogP3: 0.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 147.07178521
• Heavy Atom Count: 9
• Complexity: 112

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCSC(C)(C)C(=O)N

Technology Process of Propionamide, 2-ethylthio-2-methyl-

There total 3 articles about Propionamide, 2-ethylthio-2-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-2-methylpropanamide (7462-74-0) + ethanethiol (75-08-1) → α-Aethylmercapto-isobuttersaeure-amid (7505-95-5)

Guidance literature:

With sodium ethanolate; at 0 ℃; mehrwoechigen Aufbewahres des Reaktionsgemisches bei Raumptemperatur;

DOI:10.1021/ja01267a047

Reference yield:

ethyl bromide (74-96-4) + 2-mercapto-2-methylpropanoic acid (4695-31-2) → α-Aethylmercapto-isobuttersaeure-amid (7505-95-5)

Guidance literature:

Multistep reaction;

DOI:10.1021/jm00340a003

Reference yield:

2-bromo-2-methylpropanamide (7462-74-0) + sodium ethanolate (141-52-6) + ethanethiol (75-08-1) → α-Aethylmercapto-isobuttersaeure-amid (7505-95-5)

Guidance literature:

at 0 ℃; und mehrwoechigem Stehenlassen des Reaktionsgemisches bei Raumtemperatur; reagiert analog mit Propyl- und Butylmercaptan;

DOI:10.1021/ja01267a047

upstream raw materials:

2-bromo-2-methylpropanamide

sodium ethanolate

ethanethiol

ethyl bromide