Hexanal phenylhydrazone

Base Information

• Chemical Name: Hexanal phenylhydrazone
• CAS No.: 6228-44-0
• Molecular Formula: C12H18 N2
• Molecular Weight: 190.28
• Mol file: 6228-44-0.mol

Synonyms:hexanal phenylhydrazone;hexanal phenylhydrazone, (E)-isomer;hexanal phenylhydrazone, (Z)-isomer

Chemical Property of Hexanal phenylhydrazone

Chemical Property:

• Vapor Pressure: 0.0104mmHg at 25°C
• Melting Point: 102-103 °C
• Boiling Point: 272°C at 760 mmHg
• PKA: 14.33±0.10(Predicted)
• Flash Point: 98.2°C
• PSA: 24.39000
• Density: 0.97g/cm³
• LogP: 3.73760
• XLogP3: 4.8
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 7
• Exact Mass: 206.141913202
• Heavy Atom Count: 15
• Complexity: 165

Purity/Quality:

97% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCCCCON=NC1=CC=CC=C1

Technology Process of Hexanal phenylhydrazone

There total 2 articles about Hexanal phenylhydrazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

hexanal (66-25-1) + phenylhydrazine (100-63-0) → n-phenylhexanal hydrazone (6228-44-0)

Guidance literature:

With 1,3-bis-n-butylimidazolium bromide; at 20 ℃;

DOI:10.1081/SCC-120027236

Reference yield:

(9E,12E)-Octadeca-9,12-dienoic acid (60-33-3,116745-32-5,26085-09-6,64080-88-2,7049-66-3,949900-18-9,60476-23-5,6144-28-1,67922-65-0,89718-18-3) → (9Z,11E,13S)-13-hydroperoxy-9,11-octadecadienoic acid (33964-75-9,18320-18-8) + n-phenylhexanal hydrazone (6228-44-0)

Guidance literature:

With oxygen; soybean lipoxygenase-1;

Reference yield:

diazodimedone (1807-68-7) + n-phenylhexanal hydrazone (6228-44-0) → C20H28N2O2

Guidance literature:

In toluene; at 140 ℃; for 0.166667h; diastereoselective reaction; Inert atmosphere; Microwave irradiation;

DOI:10.1021/ol2016669

upstream raw materials:

(9E,12E)-Octadeca-9,12-dienoic acid

hexanal

phenylhydrazine

Refernces

• 1、 Wen, Jia-Jie,Tang, Hai-Tao,Xiong, Kai,Ding, Zong-Cang,Zhan, Zhuang-Ping. "Synthesis of polysubstituted pyrazoles by a platinum-catalyzed sigmatropic rearrangement/cyclization cascade". supporting information. p. 5940 - 5943. Retrieved 2015/01/08.
• 2、 Polshettiwar, Vivek,Varma, Rajender S.. "Polystyrene sulfonic acid catalyzed greener synthesis of hydrazones in aqueous medium using microwaves". . p. 5649 - 5652. Retrieved 2008/02/10.