Acetic acid, 1-methylhydrazide

Base Information

• Chemical Name: Acetic acid, 1-methylhydrazide
• CAS No.: 3530-13-0
• Molecular Formula: C3H8N2O
• Molecular Weight: 88.1093
• NSC Number: 235817
• UNII: R6QHM8N7H9
• DSSTox Substance ID: DTXSID5073327
• Nikkaji Number: J33.465K
• Wikidata: Q82001716
• Mol file: 3530-13-0.mol

Synonyms:N-methylacetohydrazide;3530-13-0;ACETIC ACID, 1-METHYLHYDRAZIDE;1-Acetyl-1-methylhydrazine;1-Methyl-1-acetylhydrazine;1-Methyl-1-acetylhydrazide;1-Methyl-1-acetylhydrazid;1-Methyl-1-acetylhydrazid [German];NSC 235817;BRN 1740469;R6QHM8N7H9;NSC-235817;4-04-00-03328 (Beilstein Handbook Reference);1-acetyl-1-methyl hydrazine;NSC235817;UNII-R6QHM8N7H9;1-acetyl-1 methylhydrazine;Methyl-acetylhydrazine, 1-;WLN: ZN1&V1;DTXSID5073327;MFCD01672525;AKOS022504318;E85124;EN300-198080

Chemical Property of Acetic acid, 1-methylhydrazide

Chemical Property:

• Vapor Pressure: 9.71mmHg at 25°C
• Boiling Point: 130.4°C at 760 mmHg
• Flash Point: 32.7°C
• Density: 1.023g/cm³
• XLogP3: -1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 88.063662883
• Heavy Atom Count: 6
• Complexity: 61.8

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: CC(=O)N(C)N

Technology Process of Acetic acid, 1-methylhydrazide

There total 1 articles about Acetic acid, 1-methylhydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

methylhydrazine (60-34-4) + 1-phenylbutan-1,3-dione (93-91-4) → 1-methyl-1-benzoylhydrazine (1483-24-5) + N-methylacetohydrazide (3530-13-0) + 1-benzylidene-2-methylhydrazine (13466-29-0) + acetaldehyde methylhydrazone (17167-73-6)

Guidance literature:

1-phenylbutan-1,3-dione; With piperidine; pyridine; ferrocenecarboxaldehyde; acetic acid; In benzene; for 12h; Reflux;

methylhydrazine; In ethanol; at 20 ℃; Inert atmosphere;

DOI:10.1002/jhet.94

Reference yield: 80.0%

N-methylacetohydrazide (3530-13-0) + 2-oxo-N-(4-chlorophenyl)propanehydrazonoyl chloride (18247-78-4,1338563-31-7) → 5-acetyl-7-(4-chlorophenyl)-3-methyl-3,4,6,7-tetraaza-5-hepten-2-one

Guidance literature:

With triethylamine; In tetrahydrofuran; at 0 ℃;

DOI:10.1081/SCC-120018683

Reference yield: 78.0%

N-methylacetohydrazide (3530-13-0) + 10-phenylfuro<2,3-e>isoquinolino<2,1-b>-as-triazinium perchlorate → 2-(2-acetyl-2-methylhydrazono)-3-benzoylmethyl-2H-isoquinolino<2,1-b>-as-triazine (146746-11-4)

Guidance literature:

In acetonitrile; for 2h;

DOI:10.1007/BF00808281

upstream raw materials:

methylhydrazine

1-phenylbutan-1,3-dione

Downstream raw materials:

acetic acid-[methyl-(4-nitro-benzylidene)-hydrazide]

N-methyl-N'-(phenylmethylene)acetohydrazide

acetic acid-[(4-methoxy-benzylidene)-methyl-hydrazide]

Methyl-carbamic acid 2-(acetyl-methyl-hydrazonomethyl)-phenyl ester

Refernces