methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium

Base Information

• Chemical Name: methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium
• CAS No.: 115981-45-8
• Molecular Formula: C₂₉H₂₉F₃OP₂Pd
• Molecular Weight: 618.911
• Mol file: 115981-45-8.mol

Synonyms:methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium

Chemical Property of methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium

There total 2 articles about methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

dimethyl[1,2-bis(diphenylphosphanyl)ethane]palladium (63455-39-0) + 2,2,2-trifluoroethanol (75-89-8) → methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium (115981-45-8)

Guidance literature:

In toluene; Addn. of HOCH2CF3 to PdMe2(dpe) under protective gas (toluene, room temp.), stirring; addn. of hexane, filtn., recrystn. (CH2Cl2-hexane), elem. anal.;

Reference yield:

dimethyl[1,2-bis(diphenylphosphanyl)ethane]palladium (63455-39-0) + 2,2,2-trifluoroethanol (75-89-8) + trifluoroethanol-d3 (77253-67-9) → methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium (115981-45-8) + (((C6H5)2P)2CH2CH2)Pd(CH3)OCD2CF3 (1094064-07-9)

Guidance literature:

In further solvent(s); byproducts: CH4, CH3D; 294 K; Kinetics;

DOI:10.1021/ja807427d

Reference yield: 74.0%

methyl(2,2,2-trifluoro-ethoxo){1,2-bis(diphenylphosphino)ethane}palladium (115981-45-8) → 2,2,2-trifluoroethyl acetate (406-95-1)

Guidance literature:

With carbon monoxide; In tetrahydrofuran; byproducts: Pd(CO)(m)(dpe)n; Addn. of CO (ambient pressure) to metal complex (THF, room temp.), stirring (2 h),; trap-to-trap distn., GLC anal.;

upstream raw materials:

dimethyl[1,2-bis(diphenylphosphanyl)ethane]palladium

2,2,2-trifluoroethanol

trifluoroethanol-d₃

Downstream raw materials:

2,2,2-trifluoroethyl acetate

methane

ethane

2,2,2-trifluoroethanol

Refernces

• 1、 Bercaw, John E.,Chen, George S.,Labinger, Jay A.,Lin, B.-L.. "Hydrogen tunneling in protonolysis of platinum(II) and palladium(II) methyl complexes: Mechanistic implications". . p. 17654 - 17655. Retrieved 2009/06/23.